Effect of a mindfulness-based movement exercise combined with meditation on physical fitness, cognitive performance, and blood biomarkers in sedentary overweight and obese young adult women

Effect of mindfulness-based movement exercise (Baduanjin Qigong) combined with meditation on physical fitness, cognitive function, oxidative stress, and telomere length in sedentary overweight and obese young adult women: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260427010

Enrollment

Registered

2026-04-27

Start date

2026-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

young adult women with overwight and obese mindfulness exercise, cognitive performance, blood biomarkers, longevity, sedentary with overweight and obese women, sedentary with overweight and obese elderly

Interventions

Participants will undergo an 8-week mindfulness-based exercise program combining Baduanjin Qigong and meditation, performed 3 times per week (60 minutes/session). Each session includes meditation (10

Experimental Behavioral,No Intervention No treatment

Mindfulness based movement exercise combined with meditation,Usual Lifestyle (Control Group)

Eligibility

Sex/Gender

Female

Age

18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1. Female aged 18 to 30 years 2. Sedentary lifestyle less than 150 minutes per week of moderate physical activity 3. Overweight defined as BMI greater than or equal to 25 kg per m2 or obese defined as BMI greater than or equal to 30 kg per m2 4. No regular exercise program in the past 3 months 5. No antioxidant or vitamin supplementation in the past 3 months 6. Non smoker and low alcohol consumption 7. Willing to participate in the study

Exclusion criteria

Exclusion criteria: 1. Cardiovascular disease, cancer, diabetes, thyroid disorders, or other chronic illnesses 2. Psychiatric disorders (e.g., depression, insomnia) 3. Uncontrolled hypertension 4. Difficulty in blood sampling 5. Low back pain or history of spinal surgery

Design outcomes

Primary

Measure	Time frame
Physical fitness VO2max muscle strength flexibility Baseline and after 8 weeks VO2max measured by treadmill test with gas analyzer (Bruce protocol); muscle strength assessed by dynamometer and biodex; flexibility assessed by sit-and-reach test.,Cognitive performance (MoCA, Digit Span Test, Trail Making Test, Stroop Test, EEG) Baseline and after 8 weeks Cognition assessed by MoCA, Digit Span, Trail Making Test A-B, Stroop Test, and EEG (10-20 system).	—

Measure

Time frame

Physical fitness VO2max muscle strength flexibility Baseline and after 8 weeks VO2max measured by treadmill test with gas analyzer (Bruce protocol); muscle strength assessed by dynamometer and biodex; flexibility assessed by sit-and-reach test.,Cognitive performance (MoCA, Digit Span Test, Trail Making Test, Stroop Test, EEG) Baseline and after 8 weeks Cognition assessed by MoCA, Digit Span, Trail Making Test A-B, Stroop Test, and EEG (10-20 system).

—

Secondary

Measure	Time frame
Metabolic inflammatory oxidative stress antioxidant BDNF telomere HbA1c and hematological biomarkers Baseline and after 8 weeks Fasting blood analysis including lipid profile, glucose, insulin, HbA1c, CBC; biomarkers measured by ELISA or spectrophotometry; telomere length by qPCR.	—

Countries

Thailand

Contacts

Public ContactKultida Klarod

Burapha University

kultida@go.buu.ac.th038103164

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026