Effectiveness of a Home-Based Exercise and Nutrition Program on Muscle Mass, Physical Function, and Quality of Life in Older Adults with Sarcopenia: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260426001

Enrollment

Registered

2026-04-26

Start date

2026-05-01

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia Age related muscle loss Functional decline in older adults Sarcopenia Aged Exercise Therapy Resistance Training Nutrition Therapy Muscle Strength Physical Function Quality of Life

Interventions

Participants receive a 12 week home based exercise and nutrition program. The program includes resistance training three times per week for 30 to 45 minutes per session and individualized nutrition co

Experimental Behavioral,Active Comparator Other

Home Based Exercise and Nutrition Program,Usual Care

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Aged 60 years or older Diagnosed with sarcopenia based on AWGS criteria Able to walk independently with or without assistive devices Mini Mental State Examination score 24 or higher Willing to participate and provide informed consent

Exclusion criteria

Exclusion criteria: Severe cardiovascular pulmonary or musculoskeletal conditions that limit physical activity Recent hospitalization or acute illness Participation in structured exercise or nutrition program within the past 3 months Severe depression with PHQ 9 score 21 or higher Cognitive or communication impairment affecting ability to follow instructions

Design outcomes

Primary

Measure	Time frame
Hand grip strength Baseline Week 4 Week 8 Week 12 Hand dynamometer measurement,Timed Up and Go Baseline Week 4 Week 8 Week 12 Timed Up and Go test in seconds,Sit to stand test Baseline Week 4 Week 8 Week 12 Five times sit to stand test in seconds,Walking speed Baseline Week 4 Week 8 Week 12 Six meter walk test in meters per second,Muscle mass Baseline Week 4 Week 8 Week 12 Bioelectrical impedance analysis,Sarcopenia status Baseline Week 12 Assessment based on AWGS criteria	—

Measure

Time frame

Hand grip strength Baseline Week 4 Week 8 Week 12 Hand dynamometer measurement,Timed Up and Go Baseline Week 4 Week 8 Week 12 Timed Up and Go test in seconds,Sit to stand test Baseline Week 4 Week 8 Week 12 Five times sit to stand test in seconds,Walking speed Baseline Week 4 Week 8 Week 12 Six meter walk test in meters per second,Muscle mass Baseline Week 4 Week 8 Week 12 Bioelectrical impedance analysis,Sarcopenia status Baseline Week 12 Assessment based on AWGS criteria

—

Secondary

Measure	Time frame
Calf circumference Baseline Week 4 Week 8 Week 12 Tape measurement in centimeters,Body mass index Baseline Week 4 Week 8 Week 12 Weight and height calculation,Quality of life Baseline Week 12 SF 36 questionnaire	—

Countries

Thailand

Contacts

Public ContactMonthida Sangruangake

Faculty of Nursing, Udon Thani Rajabhat University

monthida2524@gmail.com0816703060

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: May 1, 2026