Efficacy of Femoral-Triangle and Genicular Nerve Blocks Compared With Adductor- Canal Block for Postoperative Analgesia After Total Knee Arthroplasty : A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260424015

Enrollment

Registered

2026-04-24

Start date

2026-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia for total knee arthroplasty Total knee arthroplasty, Femoral-Triangle block, Genicular nerve blocks, Analgesia

Interventions

Combined Femoral-Triangle and Genicular nerve blocks used 0.25% Bupivacaine 35 ml GNB 15 ml and FTB 20 ml under ultrasound guidance,Adductor-Canal block used 0.25% Bupivacaine 20 ml under ultrasound g

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

Combined Femoral-Triangle and Genicular nerve blocks ,Adductor-Canal block

Eligibility

Sex/Gender

All

Age

20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 20-75 years old 2. Undergoing elective Unipolar Total Knee Arthroplasty under spinal anesthesia 3. American Society of Anesthesiologists Physical Status (ASA) I-III 4. Able to give a written informed consent

Exclusion criteria

Exclusion criteria: 1. Patients with abnormal blood coagulation 2. Patients with contraindications to spinal anesthesia 3. Patients with contraindications to peripheral nerve block (e.g. local infection, neurologic deficit or disorder, peripheral neuropathy) 4. Patients with a history of allergy to local anesthetics or medications used in this study 5. Patients with a history of chronic opioid use for more than 3 months 6. Patients with severe renal impairment (CKD stage > 3B) or those requiring renal replacement therapy 7. Patients with severe liver failure (Child-Pugh C) 8. Patients with a body weight of less than 45 kilograms 9. Patients with a body mass index (BMI) greater than 40 kg/m2 10. Pregnant or breastfeeding patients 11. Patients unable to communicate (e.g., language barriers, severe dementia) or unable to use a Patient-Controlled Analgesia (PCA) pump 12. Patients undergoing revision knee surgery 13. Patients with a history of knee surgery or prior trauma on the same side as the planned surgery

Design outcomes

Primary

Measure	Time frame
Total opioid consumption 24 hours postoperatively Patient-controlled analgesia	—

Secondary

Measure	Time frame
Pain score 6 12 and 24 hours postoperatively Numeric Rating Scale	—

Countries

Thailand

Contacts

Public ContactNudtapod Rutanaburee

Faculty of Medicine, Srinakarinwirot university

nurngnoi@gmail.com0858184868

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026