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A digitally integrated multimodal intervention lowers occupational stress and improves heart-rate variability in ICU nurses: A randomized trial

A digitally integrated multimodal intervention lowers occupational stress and improves heart-rate variability in ICU nurses: A randomized trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260423006
Enrollment
122
Registered
2026-04-23
Start date
2025-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Occupational Stress Burnout, Psychological Anxiety Depression Digital technology-based

Interventions

A 4-week digitally integrated multimodal intervention consisting of: (1) online mindfulness-based stress reduction training via a mobile digital platform (weekly structured modules including mindfulne
(2) 3D-guided meditation using VR headsets (PlayStation VR2) before each shift change to create an immersive relaxation experience
and (3) motion-based videogames (Ring Fit Adventure on Nintendo Switch) featuring fat burning, breathing regulation, and yoga relaxation activities. Interventions are delivered Monday through Thursday
s psychological counseling room via appointment scheduling, allowing nurses to voluntarily request individual counseling sessions
and (2) routine humanistic care interventions including one weekly psychological lecture (45-60 minutes), weekly heart-to-heart talks with ward head nurses during the first three weeks, and a Nursing
Experimental Behavioral,Active Comparator Behavioral
Digital Multimodal Intervention,Routine Psychological Intervention

Sponsors

Wei Guo
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.ICU nurses with Perceived Stress Scale (PSS) score greater than or equal to 29 2.Hold a valid nursing license 3.At least one year of ICU nursing experience 4.No prior exposure to multimodal stress reduction interventions 5.Provide voluntary informed consent and agree to fully participate in the intervention

Exclusion criteria

Exclusion criteria: 1.Interns or trainee nurses 2.History of psychiatric disorders 3.Major life changes during the study period 4.Concurrent participation in other psychological counseling programs 5.On maternity leave during the intervention period

Design outcomes

Primary

MeasureTime frame
Occupational_Stress_PSS Baseline, 4 weeks (intervention end), 8 weeks (1-month follow-up) Perceived Stress Scale (PSS), measuring sense of tension and loss of control. Higher scores indicate greater occupational stress.,Heart_Rate_Variability_SDNN Baseline, 4 weeks (intervention end), 8 weeks (1-month follow-up) Standard deviation of normal-to-normal intervals (SDNN) from heart rate variability. Higher SDNN indicates lower physiological stress.

Secondary

MeasureTime frame
Anxiety_SAS Baseline, 4 weeks (intervention end), 8 weeks (1-month follow-up) Self-Rating Anxiety Scale (SAS). Higher scores indicate greater anxiety.,Depression_SDS Baseline, 4 weeks (intervention end), 8 weeks (1-month follow-up) Self-Rating Depression Scale (SDS). Higher scores indicate greater depression.,Self_Efficacy_GSES Baseline, 4 weeks (intervention end), 8 weeks (1-month follow-up) General Self-Efficacy Scale (GSES). Higher scores indicate greater self-efficacy.,Well_Being_IWB Baseline, 4 weeks (intervention end), 8 weeks (1-month follow-up) Index of Well-being (IWB). Higher scores indicate greater well-being.

Countries

China

Contacts

Public ContactWei Guo

Nanjing Pukou People's Hospital

Gw15051804310@163.com02558532829

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026