Lung Ultrasound to Predict Successfully Discontinue Non-invasive Ventilation in Very Preterm Infants

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20260420010

Enrollment

Registered

2026-04-20

Start date

2024-12-26

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung ultrasound score value that can predict successful weaning from the first trial of non-invasive ventilation in preterm infants. lung ultrasound, preterm infant, , weaning off NIV

Interventions

a population with PMA at least 32 weeks with successful weaning off NIV at first trial,a population with PMA at least 32 weeks with failed weaning off NIV at first trial

Diagnostic,Diagnostic

successful weaning off NIV at first trial,failed weaning off NIV at first trial

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Newborn infants with gestational age < 32 weeks OR birth weight < 1,500 g. 2. Infants requiring respiratory support (either invasive mechanical ventilation or NIV such as nCPAP/NIPPV). 3. Parents or legal guardians provide written informed consent.

Exclusion criteria

Exclusion criteria: 1. Major chromosomal abnormalities (Trisomy 13, 18, or 21) or other life-threatening genetic conditions. 2. Congenital anomalies affecting lung function (e.g., congenital diaphragmatic hernia, congenital pulmonary airway malformation). 3. Significant congenital heart disease, excluding patent ductus arteriosus and simple atrial or ventricular septal defects.

Design outcomes

Primary

Measure	Time frame
finding a cut-off Determine the cut-off value of the lung ultrasound score that can predict successful weaning from the first trial of non-invasive ventilation. at day of life 7, 14, since PMA 32 then every week until trial off NIV. Lung ultrasound score	—

Secondary

Measure	Time frame
determine the relation between lung ultrasound score value and post-menstrual age that can predict successful weaning from the first trial of NIV. at the first trial of NIV weaning Lung ultrasound score,Identify the factors associated with successful weaning from NIV. - factors	—

Countries

Thailand

Contacts

Public ContactPunnanee Wutthigate

Faculty of Medicine Siriraj Hospital, Mahidol University

punnanee.wut@mahidol.edu66659400902

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026