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The Effect of Advanced Practice Nurse-Led Self-Management Enhancing Program on Body Composition, Physical Function, Fatigue, and Quality of Life in Gastrointestinal Cancer Patients with Cachexia

The Effect of Advanced Practice Nurse-Led Self-Management Enhancing Program on Body Composition, Physical Function, Fatigue, and Quality of Life in Gastrointestinal Cancer Patients with Cachexia

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260420007
Enrollment
40
Registered
2026-04-20
Start date
2024-08-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal cancer GI cancer1

Interventions

Nutrition: Personalized nutritional support and monitoring. Exercise: Structured physical activity/exercise regimen. Counseling: Professional nursing counseling focused on self-care agency.,Participan
s protocols without the supportive-educative program.
Experimental Behavioral,No Intervention Behavioral
Supportive-Educative Nursing Program,Standard Care Group

Sponsors

Faculty of Medicine Ramathibodi Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Age 18 years and older. 2) Screened for cancer cachexia using a weight loss of >5% within 6 months, unrelated to starvation, or >10% within 6 months or more, or >2% weight loss along with a BMI of less than 18.5 kg/m2 if under 70 years of age. For those over 70 years of age, the criteria were less than 20 kg/m2. 3) Good level of consciousness, able to communicate in Thai, and without any communication difficulties. 4) Free from depression, as assessed by the Thai Depression Screening Tool (2Q), and willing to participate in this study. 5) Those aged 60 years and older have a score of more than 3 on the Mini-Cog cognitive impairment test. 6) The Eastern Cooperative Oncology Group's performance status assessment is 0-2. 7) For surgical cases, the patient must have undergone surgery at least six weeks prior. 8) Patients with no history of comorbidities, including heart failure, chronic obstructive pulmonary disease, neurological disorders, or musculoskeletal limitations, were included.

Exclusion criteria

Exclusion criteria: 1) Exclusion criteria: Participants did not follow the research project procedures, significantly affecting data interpretation. 2) Inability to swallow food or receive nutrition via a feeding tube or intravenously. 3) Implanted pacemakers or defibrillators. 4) Ede-ma or ascites.

Design outcomes

Primary

MeasureTime frame
Physical Function: Functional Capacity (6-Minute Walk Test) Baseline and 12 weeks post-intervention 6-Minute Walk Test (6MWT)

Secondary

MeasureTime frame
Physical Function: Upper Limb Muscle Strength (Handgrip Strength) Baseline and 12 weeks post-intervention Handgrip Strength: Handheld Dynamometer measured in kilograms.,Body composition Baseline and 12 weeks post-intervention Body Composition: BIA in kilograms/percent,Fatigue Baseline and 12 weeks post-intervention The cancer fatigue scale,Quality of Life Baseline and 12 weeks post-intervention Quality of Life: FAACT scale.

Countries

Thailand

Contacts

Public ContactSuchira Chaiviboontham

Ramathibodi School of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University

suchira.cha@mahidol.ac.th022010694

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026