splenic stiffness measurement and presence of varices in patients with advanced chronic liver disease splenic stiffness measurement, varices, advanced chronic liver disease
Conditions
Interventions
patients with esophageal or gastric varices, confirmed with EGD,patients without esophageal or gastric varices, confirmed with EGD
Diagnostic,Diagnostic
presence of varices patients,no varices patients
Sponsors
Faculty of Medicine Vajira Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. patients diagnosed advanced chronic liver disease by imaging (ultrasonography, computer tomography, or magnetic resonance imaging), or liver biopsy or liver stiffness of at least 15 kPa 2. patients performed or planned to perform EGD within 4 months
Exclusion criteria
Exclusion criteria: 1. denied to perform EGD or SSM 2. history of splenectomy or congenital asplenia 3. non-cirrhotic portal hypertension 4. portal vein thrombosis or history of splenic vein embolization 5. history of esophageal varices rubber band ligation or gastric varices glue injection within 1 year prior to inclusion 6. presence of ascites 7. acute on chronic liver failure 8. HCC without treatment or with treatment other than surgical resection 9. BMI equal or more than 35 kg/sq.m.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SSM, LSM, ANTICIPATE-NASH score within 3 months of EGD VCTE Fibroscan, ANTICIPATE-NASH model | — |
Secondary
| Measure | Time frame |
|---|---|
| SSM combined with ANTICIPATE-NASH score Within 3 months of EGD VCTE Fibroscan, ANTICIPATE-NASH model | — |
Countries
Thailand
Contacts
Public ContactKwanchat Krairaweengarmiwjitr
Department of Medicine Faculty of Medicine Vajira Hospital Navamindradhiraj University
Outcome results
None listed