Postoperative delirium (POD) following general anesthesia in elderly patients aged 65-100 years, with intraoperative anesthesia monitored using standard monitoring (control group), Bispectral Index (BIS group), or density spectral array (DSA group). Elderly Postoperative Postoperative delirium Bispectral index Density spectral array Monitoring General anesthesia
Conditions
Interventions
Patients in this group serve as the control group, receiving general anesthesia with standard intraoperative monitoring alone, including non-invasive blood pressure, electrocardiography (EKG), and pul
No Intervention Device,Experimental Device,Experimental Device
Control group,BIS group,DSA group
Sponsors
Faculty of Medicine Siriraj Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 65-100 years at Siriraj Hospital scheduled for non-emergency, non-cardiac surgery. 2. Patients undergoing surgery lasting at least 1 hour under general anesthesia. 3. Patients admitted postoperatively for at least 2 days. 4. Patients with American Society of Anesthesiologists (ASA) physical status I-III.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of allergy to injectable or inhaled anesthetics or any other drugs used in the study. 2. Patients unable to communicate in or understand Thai, or with significant communication limitations (e.g., severe visual or hearing impairment, or endotracheal intubation). 3. Patients with preexisting acute delirium before surgery. 4. Patients with epilepsy or Parkinsons disease requiring antiepileptic or antiparkinsonian medications that may affect postoperative delirium. 5. Patients with a Richmond Agitation-Sedation Scale (RASS) score of -4 or -5 prior to postoperative delirium assessment. 6. Patients with conditions affecting cognition or mental status, including chronic alcohol use, chronic opioid use, psychiatric disorders, depression, dementia, or use of psychoactive medications. 7. Patients with incomplete medical records, including essential data on medical history, physical examination, anesthesia, surgery, and nursing documentation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirum (POD) preoperative, postoperative day 1, and postoperative day 2 incidence of postoperative delirium (POD) | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactPawit Somnuke
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed