Chronic obstructive pulmonary disease Pulmonary Disease, Chronic Obstructive
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meet the GOLD guidelines for the diagnosis of stable moderate-to-severe COPD 10, with a forced expiratory volume in the first second/forced vital capacity FEV1/FVC less than 0.70 for confirmation, and FEV1% predicted between 30 percent and 80 percent to determine moderate-to-severe severity; (2) Age 18 years or older; (3) Patients able to cooperate with pulmonary function tests; (4) Adequate oxygenation: Oxygenation index greater than 150 mmHg with inhaled oxygen concentration 40 percent or less and positive end-expiratory pressure 5 cm H2O or less; (5) Hemodynamically stable; (6) Voluntary participation in this study and signing of informed consent.
Exclusion criteria
Exclusion criteria: (1) Mental or intellectual disabilities preventing normal communication; (2) Liver or kidney dysfunction; (3) Concurrent malignant tumors or end-stage disease (expected survival time <7 days); (4) Other respiratory diseases; (5) Poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The 6-minute walk distance After 4 weeks of intervention The subject is required to walk back and forth along a flat, unobstructed, and well-ventilated corridor measuring 30 meters in length. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chronic obstructive pulmonary disease assessment test After 4 weeks of intervention Based on factors including cough, sputum volume, degree of chest tightness, shortness of breath when climbing stairs, physical labor, outdoor activities, energy levels, and sleep quality,St. George's respiratory questionnaire After 4 weeks of intervention This scale comprises three dimensions: symptoms, activity, and impact on daily life, containing a total of 50 items,Barthel index After 4 weeks of intervention To assess the patient's level of fatigue, the total score ranges from 0 to 10 points, with 0 points indicating no fatigue and 10 points indicating extreme fatigue.,Borg scale scores After 4 weeks of intervention It is used to assess dyspnea or fatigue. | — |
Countries
China
Contacts
Quzhou People's Hospital