Effectiveness of Gamified Reality Video Observed Therapy (GRVOTS) For Tuberculosis Medication Adherence among Adult Tuberculosis Patients in Klang Valley

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260411006

Enrollment

Registered

2026-04-11

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult patients with pulmonary tuberculosis who are required to adhere to anti-tuberculosis medication by Gamified Reality Video Observed Therapy(GRVOTS) or Direct Observed Treatment Short-course (DOTS TB diary). Pulmonary tuberculosis, tuberculosis, Gamified Reality Video Observed Therapy, Direct Observed Treatment Short-course

Interventions

If the adult TB patient is randomised into GRVOTS arm, he will be asked to download GRVOTS mobile health app on smartphone. Tutorial on how to operate GRVOTS will be given to the trained member of TB

Experimental Device,Active Comparator Device

Gamified Reality Video Observed Therapy (GRVOTS) mobile health application,Direct Observed Treatment Short-course (DOTS) TB diary

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Newly diagnosed PTB with first line anti-TB medication 2. Newly diagnosed PTB sputum AFB positive 3. Able to speak Malay and English 4. Willing and able to provide informed consent 5. Health clinics with minimum 10 TB cases

Exclusion criteria

Exclusion criteria: 1. Patients with drug-resistance TB 2. Patients with intolerance to anti-TB medication first two weeks of treatment (Garfein & Doshi, 2019) 3. Patients with arthritis/ vision impairment that hinders the usage of smartphone. 4. Health clinics with no TB cases

Design outcomes

Primary

Measure	Time frame
Adherence score week 0, week 2, week 4, week 6, week 8, week 12, week 16, week 20, week 24, week 28 Questionnaire: Malaysia Medication Adherence Rate Scale questionnaire (MyMAAT),Adherence rate week 0, week 2, week 4, week 6, week 8, week 12, week 16, week 20, week 24, week 28 Video count checklist	—

Secondary

Measure	Time frame
Treatment outcomes week 0, week 8, week 24, week 28 Treatment outcome checklist,Sputum Acid Fast Bacilli (AFB) conversion Week 2, week 8, week 24, week 28 Sputum AFB conversion checklist,Intrinsic Motivation Inventory Score week 0, week 2, week 4, week 8, week 12, week 16, week 20, week 24, week 28 Questionnaire: Intrinsic Motivation Inventory	—

Countries

Malaysia

Contacts

Public ContactNurul Amirah Abdul Manab

Universiti Teknologi MARA (UiTM), Cawangan Sungai Buloh

amirahmanab@gmail.com0173363959

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026