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Effect of mineral water versus reverse osmosis water consumption on blood pressure level in hypertensive individuals. A randomized crossover trial

Effect of mineral water versus reverse osmosis water consumption on blood pressure level in hypertensive individuals. A randomized crossover trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260410003
Enrollment
34
Registered
2026-04-10
Start date
2026-04-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension Hypertension Mineral waters Drinking water

Interventions

First, The participants in Arm1 will consume natural mineral water at a daily volume of 1.5 liters for a total duration of 4 weeks. The mineral concentrations per liter of the study water are as follo
Active Comparator Other,Placebo Comparator Other
Mineral water,RO water

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Male and female participants aged between 30 and 60 years, 2. Currently receiving treatment for hypertension at the Primary care unit in Nakhon Sawan Province, 3. Voluntary agreement to participate in the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Uncontrolled hypertension, BP more than 180/110 mmHg, or presenting with pre-critical symptomatic hypertension (PSH), 2. secondary hypertension, 3. Presence of hypertension-mediated organ damage (HMOD), 4. There is medical condition requiring fluid restriction, such as Chronic Kidney Disease (CKD) Stage 4 or higher, Heart Failure, or Cirrhosis, 5. Pregnancy, 6. Current use of oral contraceptives or Hormone Replacement Therapy (HRT), 7. Current use of dietary supplements containing sodium, potassium, calcium, or magnesium, 8. Laboratory results from medical records within the past 3 months showing eGFR < 30 mL/min/1.73m2 or serum levels of Na, K, Ca, or Mg outside the normal reference range.

Design outcomes

Primary

MeasureTime frame
Blood pressure after week 4th and 10th (after each intervention) Blood pressure levels in mmHg

Secondary

MeasureTime frame
None None None

Countries

Thailand

Contacts

Public ContactPhanuniwit Boonnuam

Dhurakij Pundit University

68130658@dpu.ac.th0655429144

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026