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THE EFFECTS OF AN ONLINE FAMILY PSYCHOEDUCATION PROGRAM ON EXPRESSED EMOTION OF FAMILY MEMBERS AND MEDICATION ADHERENCE OF PATIENTS WITH FIRST- EPISODE SCHIZOPHRENIA

The effects of family psychoeducation program via line application on expressed emotion of family members and medication adherence of patients with first-episode schizophrenia: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260410002
Enrollment
56
Registered
2026-04-10
Start date
2025-05-26
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High family expressed emotion and poor medication adherence are powerful predictors of relapse in patients with first episode of schizophrenia. Mobile -based family psychoeducation has been accepted as effective intervention in addressing these factors. Mobile -based family psychoeducation Expressed emotion Medication adherence First-episode schizophrenia Randomized controlled trial

Interventions

A structured 7 week Online Psychoeducation Program delivered via the LINE application. The program was developed based on the Vulnerability Stress Model and aimed to reduce expressed emotion among fam
Experimental Behavioral,No Intervention No treatment
Mobile based family psychoeducation program ,Control Group

Sponsors

Faculty of Nursing, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for patients were1) a diagnosis of schizophrenia according to the International Classification of Diseases, 10th Revision ICD-10 (F20.00 to F20.09), with a duration of illness not exceeding five years from the date of initial diagnosis 2) received oral antipsychotic treatment for at least 6 months but no longer than five years 3) aged between 18 to 35 years. 4) mild psychotic symptoms severity, defined as a total score of 18 to 36 on the Brief Psychiatric Rating Scale (BPRS) 5) documented history of medication non-adherence, as recorded in medical records 6) availability of a primary caregiver and 7) ability to communicate in Thai and via telephone using the LINE application Inclusion criteria for family members were 1) being a family member living in the same household as the patients and serving as the primary caregiver for at least six months without financial compensation 2) Aged 20 to 60 years 3) ownership of a mobile phone capable of using the LINE application; 4) no prior participation in family psychoeducation programs 5) ability to speak, read, and write Thai 6) no history of psychiatric disorders, including schizophrenia, bipolar disorder, or major depressive disorder.

Exclusion criteria

Exclusion criteria: Exclusion criteria for both patients and caregivers were 1) acute exacerbation of psychotic symptoms requiring hospitalization during the study period 2) missing one or more scheduled intervention sessions 3) inability of the researcher to contact the family caregiver within one week despite repeated attempts.

Design outcomes

Primary

MeasureTime frame
Expressed Emotion at 1 week after end of the intervention The Thai Expressed Emotion Scale (TEES)

Secondary

MeasureTime frame
Medication Adherence at 1 week after end of the intervention Medication Adherence Report Scale (MARS)

Countries

Thailand

Contacts

Public Contactareerat yongprasert

Faculty of Nursing, Mahidol University

areerat.yon@student.mahidoi.ac.th025287800

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026