Enhancing Healing in Chronic Vascular Wounds with activated Platelet-Rich Plasma using autologous serum: A Prospective Randomized Study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260407007

Enrollment

Registered

2026-04-07

Start date

2026-01-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic vascular wound Platelet-Rich Plasma, PRP, activated PRP, chronic vascular wound, vascular wound, arterial ulcer wound, Diabetic wound, Venous ulcer

Interventions

Autologous activated platelet rich plasma,Standard local wound care with normal saline

Experimental Procedure/Surgery,No Intervention No treatment

PRP group,Standard wound care

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Chronic vascular wound(Arterial,Venous or mixed etiology) 2.Documented negative wound culture 3.Wound area >= 2 CM2 4.Consented autologous PRP 5.No platelet dysfunction(Platelet count > 100k)

Exclusion criteria

Exclusion criteria: 1.Infected wound 2.Malignant wound 3.Depth of wound involved bone tendon 4.Pregnancy 5.Ongoing chemotherapy treatment 6.Severe renal and hepatic failure 7.Previous treatment of PRP

Design outcomes

Primary

Measure	Time frame
wound area reduction 8 weeks Wound area	—

Secondary

Measure	Time frame
Safety of PRP 8 weeks Side effect	—

Countries

Thailand

Contacts

Public ContactPunmile Chantrapuntakul

Srinagarind hospital

miles.punmile@gmail.com0838141881

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026