Chronic Obstructive Pulmonary Disease Chronic Obstructive Pulmonary Disease Vitamin D HDAC2
Conditions
Interventions
Participants received oral Vitamin D cholecalciferol at a dose of 5000 IU daily for 3 months.
Experimental Dietary Supplement
Vitamin D Supplementation
Sponsors
Universitas Nahdlatul Ulama Surabaya
Eligibility
Sex/Gender
Male
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1). Diagnosed with COPD stage GOLD 2 and GOLD 3, 2). COPD patients who regularly seek treatment and receive standard bronchodilator therapy, 3). Willing to sign informed consent, 4). Patients with 25(OH)D levels < 32 ng/ml, 5). Male gender aged 40-80 years, 6). Normal liver function, 7). Normal kidney function
Exclusion criteria
Exclusion criteria: 1). Suffering from respiratory diseases other than COPD, 2). Allergy to vitamin D
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HDAC2 levels Baseline and 3 months ELISA | — |
Secondary
| Measure | Time frame |
|---|---|
| Pulmonary Function Tests Baseline and 3 months vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), and FEV1/FVC ratio | — |
Countries
Indonesia
Contacts
Public ContactAkbar Muhammad
Universitas Nahdlatul Ulama Surabaya
Outcome results
None listed