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Traditional epidural steroid injections vs a new cocktail that combines steroid with Lidocaine and Nalbuphine in lumbar spinal stenosis: A double-blind randomized control trial

Traditional epidural steroid injections vs a new cocktail that combines steroid with Lidocaine and Nalbuphine in lumbar spinal stenosis: A double-blind randomized control trial

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260402001
Enrollment
52
Registered
2026-04-02
Start date
2025-12-30
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal stenosis Spinal stenosis

Interventions

Use 40 mg of Triamcinolone + 1 ml of 1% Lidocaine without Adrenaline + 1 ml NSS for transforaminal epidural injection,Use 40 mg of Triamcinolone + 1 ml of 1% Lidocaine without Adrenaline + 10 mg of Na
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
Control group,Nalbuphine group

Sponsors

Navamindaradhiraj University Research Fund
Lead Sponsor
NO secondary sponser
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-80 yrs 2. Spinal stenosis with radiculopathy and correlation with MRI 3. Failed conservative after physical therapy after 6 wks (VAS decrease less than 15)

Exclusion criteria

Exclusion criteria: 1. Allergy to lidocaine, opioid, or other medications which in same as previous group 2. Previously treat with epidural steroid injection or spinal surgery 3. Any clinical indication for surgery 4. Malignant neoplasm or infection invole spine 5. Uncontrolled underlying disease 6. Pregnancy or breastfeeding status 7. Morbid obesity

Design outcomes

Primary

MeasureTime frame
VAS score for pain postop, 1 month, 3 months and 6 months Numerical scales

Secondary

MeasureTime frame
VAS score for paresthesia postop, 1 month, 3 months and 6 months Numerical scales,Oswestry disability index postop, 1 month, 3 months and 6 months Numerical scales

Countries

Thailand

Contacts

Public ContactKalyakorn Louhsatana

Faculty of medicine Vajira hospital Navamindradhiraj university

kalyakorn.lou@nmu.ac.th0840033533

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026