Facial seborrheic dermatitis allergic contact dermatitis, contact allergy, facial dermatitis, patch test, seborrheic dermatitis
Conditions
Interventions
Patients aged 18 years or older diagnosed with seborrheic dermatitis on the face for at least 6 months. This group includes individuals who do not respond to standard treatments or experience disease
Diagnostic,Diagnostic
Case/Study Group,Control/Comparison Group
Sponsors
Faculty of Medicine, Srinakharinwirot University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years or older, 2. Patients diagnosed with facial seborrheic dermatitis for at least 6 months who are refractory to standard treatment or experience recurrence. Recurrence is defined as the reappearance of clinical symptoms or lesions consistent with seborrheic dermatitis including erythema itching and greasy scales at the glabella area nasolabial fold and frontal hair line within 6 months despite receiving standard treatment, 3. Patients who are willing to participate in the study able to undergo testing and attend all follow up visits and provide written informed consent by signing the consent form
Exclusion criteria
Exclusion criteria: 1. Patients with facial rashes that do not meet the criteria for seborrheic dermatitis, such as erythematous pruritic rashes located outside the glabella area, nasolabial fold, and frontal hair line., 2. Patients with any contraindications for patch testing, including: a) Severe dermatitis. b) Use of systemic immunosuppressants such as corticosteroids, methotrexate, azathioprine, or cyclosporine within 4 weeks prior to enrollment. c) Active rashes on the back or other designated test sites. d) History of ultraviolet radiation therapy or sunburn at the test sites within 21 days prior to enrollment. e) Use of topical corticosteroids at the test sites within 14 days prior to enrollment., 3. Pregnant or breastfeeding women., 4. Patients with a history of anaphylaxis to any substance or medication, particularly substances in the SWU standard series and SWU vehicle., 5. Patients with a history of hypersensitivity to surgical skin markers, medical adhesive tapes, or waterproof dressings.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of positive patch test reactions At 72-hour, and 168-hour after the application of the patch test. The percentage of patients who have at least one positive reaction to the tested allergens. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of allergen profiles between facial SD and non-SD patients At 72-hour, and 168-hour after the application of the patch test. Number and frequency (percentage) of each specific allergen identified in both groups.,Clinical relevance of positive patch test reactions At 168-hour after patch test application. Categorization of positive reactions into 'definite', 'probable', 'possible', 'past relevance', or 'not relevant' based on patient history. | — |
Countries
Thailand
Contacts
Public ContactChotinij Lertphanichkul
Department of Dermatology, Faculty of Medicine, Srinakharinwirot University
Outcome results
None listed