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Efficacy and Safety of Acupuncture plus Acupoint Ultrasound for Acute Peripheral Facial Palsy

Acupuncture Combined with Ultrasound versus Acupuncture Alone in Acute Peripheral Facial Palsy: An Assessor-Blinded Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260401022
Enrollment
60
Registered
2026-04-01
Start date
2025-01-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peripheral facial palsy Facial Paralysis Acupuncture Therapy Ultrasonic Therapy Quality of Life Mental Health

Interventions

The treatment course comprised 10 sessions. 5 consecutive days, a 2-day break, then another 5 consecutive days. Acupuncture was applied to LI4 (Hegu), ST36 (Zusanli), ST6 (Jiache), ST4 (Dicang), BL2
Active Comparator Other,Active Comparator Other
Acupuncture ,Acupuncture combined with acupoint ultrasound

Sponsors

The Fourth People's Hospital of Kunshan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Diagnosis of unilateral acute peripheral facial palsy based on established neurological criteria; 2.Onset of symptoms within 7 days; 3.Baseline Sunnybrook Facial Grading System score not exceeding 60 (moderate to severe dysfunction); 4.Able to complete all assessments.

Exclusion criteria

Exclusion criteria: 1.Central or secondary facial paralysis (e.g., stroke, trauma, tumor); 2.Severe comorbidities (cardiovascular, hepatic, renal diseases); 3.Patients with psychiatric disorders or cognitive impairment; 4.Pregnancy or lactation; 5.Contraindications to acupuncture (bleeding disorders, needle phobia) or ultrasonic therapy (local skin infection, metal implants at site); 6.Facial paralysis previously treated with other methods or currently under treatment.

Design outcomes

Primary

MeasureTime frame
Facial nerve performance Baseline, mid-intervention,end-intervention,3-month follow-up Sunnybrook Facial Grading System

Secondary

MeasureTime frame
Quality of life in individuals with facial paralysis Baseline, 3-month follow-up Facial Clinimetric Evaluation,Anxiety and depression in medical populations Baseline, 3-month follow-up Hospital Anxiety and Depression Scale

Countries

China

Contacts

Public ContactXiaoyan Ding

The Fourth People's Hospital of Kunshan

842441390@qq.com8618888186679

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026