Pessary-induced vaginal abrasion/ulcers Pessary Vaginal abrasion/ulcers Sucralfate
Conditions
Interventions
Intravaginal sucralfate suspension application with temporary pessary removal and then follow up wound healing at 2 weeks and 4 weeks
Experimental Drug
Sponsors
Faculty Of Medicine, Prince Of Songkhla University
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age more than 18 years 2. On vaginal pessary to treat pelvic organ prolapse (POP) more than 1 week 3. Pessary-induced vaginal ulcer or abrasion 4. No vaginal estrogen in the last more than 4 weeks
Exclusion criteria
Exclusion criteria: 1. Patient refusal 2. Sucralfate allergy, aluminum compound allergy, sulfate compound allergy 3. Suspected ulcer from malignancy 4. Clinically evident sexual transmitted diseases 5. Immunocompromised ex. Active SLE, HIV CD4 < 200, poor control DM 6. Advanced kidney disease 7. Denied to follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing of pessary induced vaginal ulcers 2 weeks and 4 weeks Ulcer margin identification and imaging, calculate the number of pixels within the delineated ulcer area and convert this value into square centimeters using a fixed ratio | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events 2 weeks and 4 weeks patient-reported questionnaire | — |
Countries
Thailand
Contacts
Public ContactKrittiporn Mahachiraphat
2nd Floor, Research Innovation and Medical Education Building, Faculty of Medicine, Prince of Songkla University
Outcome results
None listed