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Impact of particulate matter 2.5 (PM2.5) on major cardiovascular outcomes among patients with acute coronary syndrome

Impact of particulate matter 2.5 (PM2.5) on major cardiovascular outcomes among patients with acute coronary syndrome

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20260401017
Enrollment
3725
Registered
2026-04-01
Start date
2026-02-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute coronary syndrome acute coronary syndrome (ACS) particulate matter 2.5 (PM2.5) percutaneous coronary intervention (PCI) major adverse cardiovascular events (MACE)

Interventions

Patient diagnosed with acute coronary syndrome (ACS) based on conventional diagnostic criteria.
Prevention
ACS patients

Sponsors

Faculty of Medicine, Chiang Mai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patient who was enrolled and signed consent to CMU-ACS registry 2. Adults aged 20 years or older are diagnosed with acute coronary syndrome (ACS) based on conventional diagnostic criteria, as documented in the CMU ACS Registry, and who have experienced major adverse cardiovascular events (MACE). 3. A clearly written date of MACE so that it can be linked to daily PM2.5 data. 4. The residential address or location at the time of the ACS incident can be found so that it can be linked to the PM2.5 monitoring site or area-level exposure.

Exclusion criteria

Exclusion criteria: 1. Patients not recorded in the CMU ACS Registry. 2. Patients who relocated or resided in areas where PM2.5 exposure cannot be accurately assessed/estimated.

Design outcomes

Primary

MeasureTime frame
Major Adverse Cardiovascular Events Major Adverse Cardiovascular Events time point Events,Short-Term exposure to PM2.5 Major Adverse Cardiovascular Events time point micrograms per cubic meter

Secondary

MeasureTime frame
Myocardial infarction Major Adverse Cardiovascular Events time point Events,Stroke Major Adverse Cardiovascular Events time point Events,Heart Failure Hospitalization Major Adverse Cardiovascular Events time point Events,All-Cause Death Major Adverse Cardiovascular Events time point Events

Countries

Thailand

Contacts

Public ContactNoppadon Yolsiritum

Faculty of Medicine, Chiang Mai University

oaty555@gmail.com66536793

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026