Diagnostic Performance of Complete Blood Count Derived Biomarkers and Clinical Scoring Systems for Predicting Complicated Appendicitis in Elderly Patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20260401005

Enrollment

Registered

2026-04-01

Start date

2019-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute appendicitis Complicated appendicitis Elderly patients Appendicitis Elderly Neutrophil to lymphocyte ratio Alvarado score RIPASA score Diagnostic accuracy

Interventions

Elderly patients aged 60 years and older diagnosed with complicated appendicitis confirmed by operative findings or pathological reports including perforation gangrene or abscess formation,Elderly pat

Diagnostic,Diagnostic

Complicated appendicitis,Non complicated appendicitis

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients aged 60 years and older Diagnosed with acute appendicitis Underwent appendectomy at HRH Princess Maha Chakri Sirindhorn Medical Center Availability of preoperative complete blood count data Availability of operative findings or pathological confirmation

Exclusion criteria

Exclusion criteria: Patients with underlying conditions affecting inflammatory markers such as cardiovascular disease diabetes mellitus hematologic disease or autoimmune disease Patients receiving non steroidal anti inflammatory drugs prior to admission Incomplete medical records or missing operative or pathological data

Design outcomes

Primary

Measure	Time frame
Diagnostic performance for predicting complicated appendicitis At diagnosis before surgery Receiver operating characteristic analysis including area under the curve sensitivity specificity and cutoff values for biomarkers and clinical scores in predicting complicated appendicitis	—

Secondary

Measure	Time frame
Independent predictors of complicated appendicitis At diagnosis Multivariable logistic regression analysis reporting odds ratios and confidence intervals for predictors of complicated appendicitis,Postoperative outcomes Within 30 days after surgery Postoperative complications 30 day mortality and length of hospital stay	—

Countries

Thailand

Contacts

Public ContactTHAWATCHAI TULLAVARDHANA

Department of Surgery, Faculty of Medicine, Srinakharinwirot University

thawatchait@g.swu.ac.th0879791989

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026