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EFFECTS OF AN ORAL MUCOSAL CARE PROGRAM ON ORAL HEALTH AND THE INCIDENCE OF VENTILATOR-ASSOCIATED PNEUMONIA IN CRITICALLY ILL CARDIAC PATIENTS: A RANDOMISED CONTROLLED TRIAL

EFFECTS OF AN ORAL MUCOSAL CARE PROGRAM ON ORAL HEALTH AND THE INCIDENCE OF VENTILATOR-ASSOCIATED PNEUMONIA IN CRITICALLY ILL CARDIAC PATIENTS: A RANDOMISED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260331001
Enrollment
60
Registered
2026-03-31
Start date
2026-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients requiring mechanical ventilation Ventilator Associated Pneumonia Oral Hygiene Mouth Mucosa Critical Care Mechanical Ventilation Intensive Care Units

Interventions

Twice daily toothbrushing using the Bass technique combined with oral mucosal care using an oral gel moisturizer. The frequency of gel application is adjusted according to the oral health assessment.
Experimental Behavioral,Active Comparator Behavioral
Oral mucosal care program,Standard oral care

Sponsors

Dara Wongkuan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Patients receiving mechanical ventilation for more than two calendar days 2. Admitted to the Cardiac Care Unit or Intermediate Cardiac Care Unit for at least 48 hours 3. Platelet count greater than 50000 cells per cubic millimeter 4. Able to read write and understand Thai language or have a close relative who can provide information 5. Provide informed consent from the patient or a legally authorized representative

Exclusion criteria

Exclusion criteria: 1. Patients with allergy to products containing fish derivatives or honey flavor 2. Patients with oral wounds or lesions 3. Patients who require reintubation within 24 hours 4. Patients who are mechanically ventilated for less than 48 hours 5. Patients diagnosed with ventilator associated pneumonia prior to enrollment 6. Patients with hemodynamic instability

Design outcomes

Primary

MeasureTime frame
Mean oral health score Daily assessment for seven days of mechanical ventilation Bedside Oral Examination score

Secondary

MeasureTime frame
Incidence of ventilator associated pneumonia Within seven days of mechanical ventilation or until extubation ventilator associated pneumonia based on clinical criteria and chest radiography

Countries

Thailand

Contacts

Public ContactDara Wongkuan

King Chulalongkorn Memorial Hospital Thai Red Cross Society

Wongkuandara@gmail.com022564570

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026