Comparison and agreement of the quantum consciousness index from the CONOX monitor between forehead and nasal bridge placement in patients undergoing craniotomy

Comparison of Quantum Consciousness Index Between Nasal Bridge and Forehead Sensor Placements in Patients Undergoing Craniotomy: A Prospective Observational Study of Agreement and Clinical Correlation

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260328001

Enrollment

Registered

2026-03-28

Start date

2026-03-31

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Craniotomy

Interventions

Apply one sensor to the forehead (according to the manufacturer&#039

s montage guide),Apply the second sensor to the nasal bridge (vertically along the midline).

Experimental Device,Experimental Device

Group 1: Forehead placement,Group 2: Nasal bridge placement

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years 2. ASA physical status I-III 3. Scheduled for elective craniotomy under general anesthesia 4. Informed consent provided

Exclusion criteria

Exclusion criteria: 1. Pre-existing neurological conditions known to affect EEG (e.g., epilepsy, severe dementia) 2. Skin lesions, inflammation, or abnormalities at the planned sensor sites 3. Pregnancy 4. Emergency craniotomy

Design outcomes

Primary

Measure	Time frame
Agreement of qCON between forehead and nasal bridge placements. During anesthesia from induction to emergence Agreement assessed using Bland Altman analysis and intraclass correlation coefficient	—

Secondary

Measure	Time frame
Agreement of EMG value / Agreement of SQI / Agreement of qNOX. During anesthesia from induction to emergence Agreement assessed using Bland Altman analysis and intraclass correlation coefficient	—

Countries

Thailand

Contacts

Public ContactNarin Plailaharn

Khon Kaen University

narinp@kku.ac.th0850119326

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026