Small airway resistance in obese obstructive sleep apnea patients Continuous positive airway pressure (CPAP), Small airway resistance, Force oscillation technique (FOT), Obese patients, Obstructive sleep apnea (OSA)
Conditions
Interventions
This study evaluated the effects of CPAP therapy on respiratory impedance (resistance and reactance) using the Forced Oscillation Technique (FOT), lung function and sleep quality in obese-OSA patient
Experimental Device
Continuous positive airway pressure
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Adult patients aged between 18 to 70 years 2.BMI more than or equal 25 3.moderate to severe OSA which RDI more than or equal 15 events/hour
Exclusion criteria
Exclusion criteria: 1.Patients with prior PAP therapy 2.Patients with history of upper airway surgery 3.Patients with abnormal baseline pulmonary function, chronic respiratory disease, or conditions affecting outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Small airway resistance (R5-R19) 1 month Force oscillation technique | — |
Secondary
| Measure | Time frame |
|---|---|
| Reactant (Xrs5), lung volumes, respiratory muscle strength, and DLCO 1 month Force oscillation technique and conventional lung function study | — |
Countries
Thailand
Contacts
Public ContactBunnapron Kittiratanawasin
Chulalongkorn university
Outcome results
None listed