Plaque-induced gingivitis Gingival inflammation Dental plaque accumulation Hemp extract mouthwash, Chlorhexidine gluconate mouthrinse, Gingivitis, Bleeding index and Plaque index
Conditions
Interventions
Participants in Arm 1 will rinse with 10 milliliters of plain water for one minute, twice daily, after breakfast and before bedtime, following the same schedule and method as the intervention groups.,
Placebo Comparator Other,Experimental Drug,Active Comparator Drug
Water (Control),Hemp Extract Mouthwash,0.12% Chlorhexidine Gluconate Mouthwash
Sponsors
Sasitharee Nathamtong, DDS, MSc, Principal Investigator
Eligibility
Sex/Gender
All
Age
20 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1.Participants must be adults aged twenty to fifty-nine years with at least twenty natural teeth. 2.Individuals must have no fixed orthodontic appliances, removable dentures, dental crowns, dental bridges, or dental implants at the time of diagnosis. 3.Participants must have no history of smoking and must not have systemic diseases affecting periodontal health. 4.Eligible participants must not be pregnant or breastfeeding. Individuals must be diagnosed with dental plaque-induced gingivitis on an intact periodontium and must demonstrate adequate oral hygiene ability. 5.Participants must be willing to attend all study visits and follow instructions throughout the trial. 6.Individuals must not have used cannabis or hemp-derived medical products during the three weeks before enrollment. 7.All participants must be able to provide written informed consent.
Exclusion criteria
Exclusion criteria: 1.Individuals will be excluded if they are not diagnosed with dental plaque-induced gingivitis on an intact periodontium or if they have poor oral hygiene ability. 2.Participants wearing fixed orthodontic appliances or having dental caries or restorations extending to the gingival margin will be excluded. 3.Individuals with a history of tooth extraction or surgical removal of impacted teeth within the past month will not be eligible. Participants with allergies to chlorhexidine or hemp-derived components will be excluded. 4.Individuals with bleeding disorders or who are taking medications that affect blood clotting will also be excluded. Participants who consumed alcohol within twenty-four hours before the procedure or who cannot cooperate with study instructions will not be eligible. 5.Individuals with behavioral or emotional disorders will be excluded from participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in gingival inflammation in patients Baseline, 7, 14 days after starting the intervention Bleeding index | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in dental plaque accumulation in patients Baseline, 7, 14 days after starting the intervention Plaque index | — |
Countries
Thailand
Contacts
Public ContactSasitharee Nathamtong
Faculty of Dentistry, Naresuan University
Outcome results
None listed