sarcopenia in patients with parkinsonism Muscles Oropharyngeal Dysphagia Parkinson Disease Sarcopenia Ultrasound Imaging
Conditions
Interventions
Patients with parkinsonism with positive clinical dysphagia screening and confirmed with abnormalities from VFSS.,Patients with parkinsonism with negative clinical dysphagia screening
Other,Other
parkinsonism with dysphagia,parkinsonism without dysphagia
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age equal or more than 65 years old 2. Patients who were diagnosed with Parkinsonism by neurologist, including idiopathic PD, atypical parkinsonian syndrome 3. Consent to participate the project
Exclusion criteria
Exclusion criteria: 1. Vital signs are unstable 2. Cognitive impairment 3. There are other neurological diseases that cause dysphagia, such as stroke, traumatic brain injury, brain tumors, cerebral palsy, severe dementia, motor neuron disease, or normal-pressure hydrocephalus. 4. There are other conditions related to the structures of the oral cavity and pharynx that cause dysphagia, such as thyroid surgery, vocal cord paralysis, head and neck cancer, or having a tracheostomy. 5. The patient has received medications or toxins that can cause parkinsonism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of sarcopenia cross sectional low muscle mass and strength,Ultrasound swallowing muscles cross sectional thickness or CSA of swallowing muscles | — |
Secondary
| Measure | Time frame |
|---|---|
| Dysphagia clinical severity cross sectional Swallowing Disturbance Questionnaire (SDQ), Repetitive Saliva Swallowing Test (RSST),nutritional status cross sectional Mini Nutritional Assessment- short form (MNA-SF),Disease severity cross sectional modified Hoenh and Yahr, The Movement Disorders Society Unified Parkinson Disease Rating Scale (MDS-UPDRS)part III, item 2.2 and 2.3, Levodopa Equivalent Dose (LEDD),cough strength cross sectional peak cough flow | — |
Countries
Thailand
Contacts
Public ContactChernkhuan Stonsaovapak
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed