Healthy adult with no active oral disease Comparative efficacy Tongue cleaning Tongue microbiota Microbiota
Conditions
Interventions
The intervention involves the use of a standardized plastic manual tongue scraper. Participants will be instructed to perform tongue cleaning once daily after regular tooth brushing before bedtime for
s head to clean the tongue surface. Participants will be instructed to perform tongue cleaning once daily after regular tooth brushing before bedtime for a duration of seve
Manual Tongue Scraper,Manual Toothbrush,Powered toothbrush
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Had an annually health check-up records with blood test result including complete blood count (CBC) and lipid profiles (total cholesterol, triglycerides, high-density lipoprotein; HDL, and low-density lipoprotein; LDL). 2. Are generally healthy and report no systemic medical conditions. 3. Have not been diagnosed with hypertension or cardiovascular disease. 4. Do not use tobacco products in any form. 5. Have not used antibiotics or antiseptic mouth rinses in the past three months. 6. Possess at least 20 natural teeth, including either the 11 and 41 or 21 and 31 teeth, with no significant periodontal deterioration. 7. Exhibit stable periodontal health, minimal bleeding on probing, and no advanced attachment loss. 8. Are free from visible oral mucosal or dental lesions. 9. Can attend scheduled study appointments and adhere to oral hygiene instructions as required.
Exclusion criteria
Exclusion criteria: 1. Have a diagnosed medical condition known to alter the oral microbiome, such as diabetes or autoimmune disorders. 2. Are currently pregnant or breastfeeding. 3. Require immediate dental intervention due to active caries or infections. 4. Have consumed probiotic supplements within the last month. 5. Present with extensive gingival inflammation, attachment loss, or bleeding at more than 10% of oral sites. 6. Use fixed orthodontic appliances or dental prosthetics that interfere with tongue hygiene procedures. 7. Report habits or routines that conflict with study requirements for oral hygiene product use. 8. Have known sensitivities to any agents used in the study, such as chlorhexidine. 9. Have a history of tongue-strengthening exercises or prior any tongue surgery. 10. Are unwilling or unable to comply with the procedures and timelines of the research protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of tongue microbiome In the morning of first visit for baseline and after finish 7 days for each type of tongue cleaning device. 16s rRNA sequencing | — |
Secondary
| Measure | Time frame |
|---|---|
| Tongue Strength At the first visits after collect tongue microbiome Using Iowa Oral Performance Instrument (IOPI) by place the air-filled tongue bulb on hard palate and press the bulb with maximum effort using the tongue. The pressure will be quantify as kilopascal.,Tongue Endurance At the first visits after collect tongue microbiome Using Iowa Oral Performance Instrument (IOPI) by place the air-filled tongue bulb on hard palate and press the bulb with 50% of maximum effort using the tongue.,Tongue Mobility At the first visits after collect tongue microbiome Using the Tongue Range of Motion Ratio (TRMR; %), calculated as the ratio of the interincisal distance during tongue-palate contact to the maximum interincisal mouth opening (MIO) | — |
Countries
Thailand
Contacts
Public ContactBoosana Kaboosaya
Department of Oral and Maxillofacial, Faculty of Dentistry Chulalongkorn University
Outcome results
None listed