Sepsis is a life-threatening condition caused by a dysregulated host response to infection, leading to organ dysfunction. Globally, it affects approximately 48.9 million people annually, accounting for 20% of all deaths. In Thailand, sepsis remains a critical public health issue with an estimated 175,000 cases and a mortality rate of 25-35%, which can exceed 50% in cases of septic shock. While traditional scoring systems like SOFA and APACHE II are used to assess severity, they often rel
Conditions
Interventions
The high-HRV group was defined based on the correlation study between various Heart Rate Variability (HRV) parameters and mortality rates. ROC curve analysis and the Youden Index were employed to iden
Diagnostic,Diagnostic
High heart rate variability group,Low heart rate variability group
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older. 2. Diagnosed with sepsis according to the Surviving Sepsis Campaign Guidelines 2021. 3. Admitted to the Intensive Care Unit (ICU).
Exclusion criteria
Exclusion criteria: 1. Patients with persistent or permanent atrial fibrillation. 2. Patients with a continuous cardiac paced rhythm (pacemaker-dependent). 3. Pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate variability 24 hours ECG monitoring | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality 28 days All cause mortality | — |
Countries
Thailand
Contacts
Public ContactSoponwich Thinwong
Faculty of Anesthesiology
Outcome results
None listed