Breast cancer related lymphedema Breast cancer related lymphedema, low level laser therapy
Conditions
Interventions
Low-Level Laser Therapy (LLLT) using the Mphi5 device with combined wavelengths of 808 nm and 905 nm in a continuous anti-edema mode at an energy density of 2 J/cm2, administered in 18 sessions over 6
therapeutic exercise to enhance the muscle pump mechanism
patient education regarding ergonomics, skin care, and precautions to optimize arm function
the use of compression garments to be worn for at least 23 hours per day
and a personalized self-management plan for lymphedema care at home.,Low-Level Laser Therapy (LLLT) using the Mphi5 device with combined wavelengths of 808 nm and 905 nm in a continuous anti-edema mod
the use of compression garments t
Experimental Device,Active Comparator Device,Sham Comparator Procedure/Surgery
Laser 2 J/cm2,Laser 4 J/cm2,Sham laser
Sponsors
Siriraj Cancer Center
Eligibility
Sex/Gender
Female
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Female 2. Over 20 years old 3. Patients with unilateral breast cancer who have undergone mastectomy 4. Diagnosed with post-operative lymphedema, Stages 1 to 3, according to the International Society of Lymphology (ISL) criteria 5. Able to participate in the entire research process and attend follow-up appointments consistently 6. No previous history of Low-Level Laser Therapy (LLLT) 7. Able to receive treatment 3 times per week 8. Not currently receiving, or planning to receive, radiation therapy or chemotherapy until the completion of the study
Exclusion criteria
Exclusion criteria: 1. Metastasis: Patients with advanced or metastatic cancer 2. Presence of cognitive impairment (Thai Mental State Examination: TMSE < 23 points) 3. Presence of bilateral arm swelling (both sides) 4. Pregnancy 5. History of Deep Vein Thrombosis (DVT) in the upper extremities 6. Presence of abnormal bleeding disorders 7. Presence of open wounds or infections at the treatment site. 8. Dermatological Conditions: Contagious skin diseases (e.g., ringworm, shingles, or scabies) 9. History of bone fractures in the affected upper extremity 10. Presence of joint prostheses in the upper extremities 11. Presence of a cardiac pacemaker 12. Renal failure 13. Pulmonary edema 14. Obesity: Class II obesity or higher (BMI > 35 kg/m2) 15. Surgical History: Previous lymphatic bypass or lymphovenous anastomosis surgery in the affected arm 16. Currently undergoing chemotherapy or radiation therapy 17. Neurological Deficits: Presence of weakness or numbness (paresthesia) in either arm 18. Nerve Injury: History of brachial plexus or nerve injury in either arm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Arm volume Baseline, 3rd week, 6th week, 12th week, 6th month Calculated by 4 levels arm circumference | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scale Baseline, 3rd week, 6th week, 12th week, 6th month Visual analog scales,Quality of life Baseline, 6th week, 12th week, 6th month Thai Lymphoedema functioning disability and health questionnaire for upper limb lymphoedema,Grip strength Baseline, 3rd week, 6th week, 12th week, 6th month Digital hand grip dynamometer,Shoulder range of motion Baseline, 6th week, 12th week, 6th month Goniometer,Satisfaction 6th week Likert scales | — |
Countries
Thailand
Contacts
Public ContactPiyapat Dajpratham
Department of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital
Outcome results
None listed