Vitamin D Supplementation for the Prevention of Gestational Diabetes Mellitus in Maharaj Nakorn Chiang Mai Hospital: A Randomized Controlled Trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260227008

Enrollment

314

Registered

2026-02-27

Start date

2026-03-17

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

GDM in pregnancy vitamin D , GDM

Interventions

Intervention Group - Product: Vitamin D3 (cholecalciferol) tablets, 600 IU per tablet (locally available). - Dose: 600 IU per day (one tablets of 600 IU) taken orally once daily with meal (recommended

Experimental Dietary Supplement,No Intervention No treatment

vitaminD,control group

Eligibility

Sex/Gender

Female

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1 Age 20 years at enrollment 2 Singleton pregnancies 3 Gestational age 15 weeks at enrollment 4 Attending antenatal care at Maharaj Nakorn Chiang Mai Hospital during the study period 5 No vitamin D deficiency

Exclusion criteria

Exclusion criteria: 1 Multiple pregnancies 2 Pre-existing diabetes mellitus (Type 1 or Type 2 diagnosed before pregnancy) 3 Use of vitamin D3 supplementation > 400 IU/day or equivalent for more than 1 month prior to enrollment 4 Condition affecting vitamin D metabolism : Women with diagnosed chronic kidney disease, liver disease, malabsorption syndromes 5 Use of medications known to interfere with glucose metabolism or vitamin D status (e.g., corticosteroid, anticonvulsant). 6 Allergy for vitamin D 7 Vitamin D toxicity 8 hypercalcemia and hyperphosphatemia.

Design outcomes

Primary

Measure	Time frame
Compare the incidence of GDM between pregnant women randomized to prophylactic vitamin D supplementation and those receiving standard antenatal care in Maharaj Nakorn Chiang Mai Hospital 2026-2027 SPSS	—

Secondary

Measure	Time frame
To evaluate the effect of oral vitamin D3 supplementation at 600 IU/day on serum 25(OH)D levels at 24-28 weeks gestation 2026-2027 SPSS	—

Countries

Thailand

Contacts

Public ContactKobkan champunot

faculty of medicine , Chiang Mai University

boomchampunot@gmail.com0825146455

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026