Postthoracotomy pain is regarded as one of the fiercest pain during perioperative periods(2). Although the minimally invasive thoracoscopic technique has been widely practiced and markedly reduced pain degree compared with traditional open-chest surgery, moderate to severe pain still takes place and proves to be associated with impaired lung secretion clearance, delayed mobilization, and delayed ventilatory recovery after surgery, prolonged hospital stays. Postthoracotomy pain
Conditions
Interventions
0.5% Bupivacaine 20 ml with morphine 3 mg,0.5% Bupivacaine 20 ml with normal saline 0.3 ml
Experimental Drug,Placebo Comparator Drug
Additional morphine to paravertebral,Additional normal saline
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1 Age 18-80 years 2 ASA physical status I-III 3 Undergoing elective video-assisted thoracoscopic surgery 4 Able and willing to provide informed consent 5 Patients appreciate to participate in this study with sign
Exclusion criteria
Exclusion criteria: 1 Contraindication of paravertebral block 2 Known allergy to any drug used on the study protocol 3 Chronic use of opioids 4 Previous thoracic surgery 5 BMI > 35 kg/m2 6Preexisting neuropathy 7 Severe DM (HbA1C>7%) 8 Severe cardiopulmonary disease 9 Severe thoracic kyphosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| median time to first analgesic request Single time Minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| the total cumulative morphine consumption via Patient-Controlled Analgesia (PCA) at 6, 12, and 24 hours postoperativel Single tine Miligram | — |
Countries
Thailand
Contacts
Public ContactSateeya Dadsanthia
Faculty of ramathibodi hospital
Outcome results
None listed