A Randomised Controlled Trial Comparing Second-Look Texture and Colour Enhancement Imaging (TXI) Versus Second-Look White Light Imaging for Adenoma Detection in the Right Colon

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260227005

Enrollment

300

Registered

2026-02-27

Start date

2026-01-25

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Detection of colorectal adenomas in the right colon during screening colonoscopy colonoscopy Colorectal cancer second-look examination

Interventions

Will undergo a second-look examination of the right colon using texture and color enhancement imaging (TXI).,Will undergo a second-look examination of the right colon using repeated white light imagin

Experimental Device,Experimental Device

Group A,Group B

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 75 years who are undergoing colonoscopy for any of the following indications 1 Colorectal cancer screening 2 Evaluation of positive faecal occult blood test 3 Evaluation of iron deficiency anaemia.

Exclusion criteria

Exclusion criteria: 1 Colorectal cancer 2 Lower gastro-intestinal bleeding 3 Pregnancy 4 Hereditary polyposis syndrome 5 Inflammatory bowel disease 6 Previous colonic surgery 7 Previous colonic obstruction 8 Previous bowel ischemia 9 Inadequate bowel preparation

Design outcomes

Primary

Measure	Time frame
Compare values After colonoscopy Adenoma detection rate	—

Secondary

Measure	Time frame
Compare values After colonoscopy Polyp detection rate (PDR) ,Compare values After colonoscopy adenoma and SSL detection rates (ASDRs),Compare values After colonoscopy mean number of adenomas per patient (MAP) ,Compare values After colonoscopy mean number of adenomas and sessile serrated lesions per patient (MASP),Compare values After colonoscopy mean number of sessile serrated lesions per patient (MSP)	—

Measure

Time frame

Compare values After colonoscopy Polyp detection rate (PDR) ,Compare values After colonoscopy adenoma and SSL detection rates (ASDRs),Compare values After colonoscopy mean number of adenomas per patient (MAP) ,Compare values After colonoscopy mean number of adenomas and sessile serrated lesions per patient (MASP),Compare values After colonoscopy mean number of sessile serrated lesions per patient (MSP)

—

Countries

Thailand

Contacts

Public ContactNattanont Pongsiriwet

Faculty of Medicine, Chiang Mai University

nattaneuu@gmail.com053936120

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026