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The efficacy of fluoride vanish application versus pit and fissure sealant in occlusal caries incidence

The efficacy of fluoride vanish application versus pit and fissure sealant in occlusal caries incidence

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260227002
Enrollment
461
Registered
2026-02-27
Start date
2024-05-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries (tooth decay) in first permanent molars of primary school children, specifically focusing on the prevention of pit and fissure caries in newly erupted first permanent molars. First permanent molar, Fluoride vanish, Sealant, ICDAS, Nyvad

Interventions

The teeth are dried by wiping, and a thin layer of fluoride varnish is applied to all tooth surfaces in the oral cavity.,1. The teeth are rinsed with water and air dried. Saliva is controlled, and the
Active Comparator Device,Active Comparator Device
Fluoride Vanish,Pit and Fissure Sealant

Sponsors

Bangkokthonburi university
Lead Sponsor
Samut Sakhon Provincial Hospital
Collaborator

Eligibility

Sex/Gender
All
Age
6 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Students with no underlying medical conditions and no intellectual or physical disabilities. 2. At least one upper or lower first permanent molar from a cooperative student whose parent or legal guardian has provided informed consent. 3. At least one upper or lower first permanent molar that has erupted into the oral cavity, with the pits and fissures completely above the gingival margin. 4. At least one upper or lower first permanent molar with deep pits and fissures. 5. At least one upper or lower first permanent molar with no detectable carious lesions.

Exclusion criteria

Exclusion criteria: 1. Students with systemic diseases. 2. Students exhibiting uncooperative behavior that prevents adequate cooperation during dental treatment. 3. First permanent molars that are partially erupted, with some pits and fissures located below the gingival margin. 4. First permanent molars with dental caries (the carious tooth will be excluded from the study; however, other fully erupted, caries-free first permanent molars in different quadrants may still be included). 5. Parent or legal guardian refusal to provide consent for treatment. 6. Students with a history of allergy to resin-based materials, fluoride, or the adhesive components of fluoride varnish.

Design outcomes

Primary

MeasureTime frame
caries incidence 24 months International Caries Detection and Assessment System (ICDAS)

Secondary

MeasureTime frame
caries incidence 24 months Nyvad Criteria for Caries Diagnosis and Lesion Activity Assessment, International Caries Detection and Assessment System (ICDAS)

Countries

Thailand

Contacts

Public ContactChanokrudee Thongchai

Faculty of dentistry, Bangkokthonburi university

nudear28@gmail.com024315383

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026