Fibrin Glue Versus Sutures for Attaching Amniotic Membrane Transplantation in Primary Pterygium Surgery

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260222001

Enrollment

Registered

2026-02-22

Start date

2024-09-27

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary pterygium Amniotic membrane transplantation, fibrin glue, pterygium, sutures

Interventions

Participants underwent pterygium excision followed by amniotic membrane transplantation. The amniotic membrane was secured to the scleral bed using fibrin glue according to standard surgical technique

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

Amniotic membrane transplantation using fibrin glue,Amniotic membrane transplantation using sutures

Eligibility

Sex/Gender

All

Age

28 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with primary pterygium. 2. Patients indicated for pterygium surgery with amniotic membrane transplantation. 3. Patients able and willing to provide informed consent and comply with the study protocol.

Exclusion criteria

Exclusion criteria: 1. Recurrent or double-head pterygium. 2. Ocular conditions that may affect surgical outcomes, including dry eye disease, glaucoma, pseudopterygium, ocular trauma, active ocular infection, or bleeding disorders. 3. Inability to comply with the follow-up schedule.

Design outcomes

Primary

Measure	Time frame
Pterygium recurrence At 6 months after surgery Slit-lamp examination to assess pterygium recurrence, defined as fibrovascular tissue regrowth extending beyond the limbus onto the clear cornea	—

Secondary

Measure	Time frame
1.Postoperative complications (such as graft loss, graft displacement, graft infection, graft hemorrhage, pyogenic granuloma) 6 months after surgery Patient-reported outcomes were assessed using clinical examinations and medical record reviews during follow-up visits.,2. Postoperative pain 2 weeks after surgery Clinical examination and medical record review, with patient-reported outcomes assessed using five-point scales during follow-up visits.,3.Patient satisfaction 6 months after surgery Clinical examination and medical record review, with patient-reported outcomes assessed using five-point scales during follow-up visits.	—

Measure

Time frame

1.Postoperative complications (such as graft loss, graft displacement, graft infection, graft hemorrhage, pyogenic granuloma) 6 months after surgery Patient-reported outcomes were assessed using clinical examinations and medical record reviews during follow-up visits.,2. Postoperative pain 2 weeks after surgery Clinical examination and medical record review, with patient-reported outcomes assessed using five-point scales during follow-up visits.,3.Patient satisfaction 6 months after surgery Clinical examination and medical record review, with patient-reported outcomes assessed using five-point scales during follow-up visits.

—

Countries

Thailand

Contacts

Public ContactAoraporn Ngaorungsee

Department of Ophthalmology, Nakhon Pathom Hospital, Ministry of Public Health, Thailand

aorapornpang@gmail.com6634240000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026