Patients undergoing benign hysterectomy gynecologic surgery (total abdominal hysterectomy with or without Salpingo-oophorectomy or Salpingectomy) hysterectomy, benign gynecologic surgery, bowel ileus, curcumin
Conditions
Interventions
The patients in the intervention group will receive the turmeric capsule the next day after surgery 500 mg 4 times/day, starting at 6.00 am., 12.00 am., 5.00 pm., 10.00 pm., then restarts the followin
Experimental Dietary Supplement,Placebo Comparator No treatment
Turmeric capsule,Placebo
Sponsors
Khonkaen hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Thai female age 18 - 80 years old who undergoing hysterectomy in benign gynecologic surgery (Total abdominal hysterectomy with or without adnexal surgery) without intra/post-operative complications (gastrointestinal organ injuries, inability to wean off the ventilator and requirement for intensive care unit). 2. Can communicate in Thai language 3. Good consciousness
Exclusion criteria
Exclusion criteria: 1. History of curcumin allergy 2. History of gastrointestinal diseases such as gastroesophageal reflux disease 3. History of carminative drugs use within 48 hrs before surgery 4. Diabetes mellitus who use antidiabetic drugs or insulin 5. Taking anticoagulant such as aspirin clopidogrel or warfarin 6. Re-operative before start intervention 7. The condition worsened and need intensive care unit 8. Have indication to restrict food intake within 24 hours after surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative bowel ileus Within 72 hours after surgery or before discharge from hospital at post operative day3 Assessed using the I-FEED score | — |
Secondary
| Measure | Time frame |
|---|---|
| the time to first flatus after surgery from end of surgery to first flatus, assessed up to 72 hours postoperatively. Time (minutes),time to first defecation after surgery from end of surgery to first defecation, assessed up to 72 hours postoperatively. Time (minutes),use of additional antiemetic drugs administered for day 2 and day 3 postoperatively. Number of rescue antiemetic doses,stomach pain assessed up to 72 hours postoperatively. Number of stomach pain episodes,diarrhea assessed up to 72 hours postoperatively. Number of diarrhea episodes | — |
Countries
Thailand
Contacts
Public ContactSiraphatson Phontham
Khonkaen hospital
Outcome results
None listed