Skip to content

Comparison the end tidal sevoflurane level which appropriate for deep laryngeal mask airway removal in patients who received dexmedetomidine intravenous injection : Randomized control trial

Comparison the end tidal sevoflurane level which appropriate for deep laryngeal mask airway removal in patients who received dexmedetomidine intravenous injection : Randomized control trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260216007
Enrollment
214
Registered
2026-02-16
Start date
2026-03-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1. When we use LMA for airway management replace endotracheal tube, we can decreased the incidence of PRAE in pediatric patients with URI 2. The incidence of PRAE in Deep LMA removal is less than Awake technique 3. Dexmedetomidine IV can decreased the need of sevoflurane for Deep LMA removal 1. Dexmedetomidine intravenous injection 2. Deep LMA removal 3. End tidal sevoflurane

Interventions

We will control the end tidal sevoflurane to level 1.07% and continue ventilate patients with this level about 10 minutes before test the level of anesthesia. If level of anesthesia is in deep level,
Experimental Drug,Active Comparator Drug
End tidal sevoflurane 1.07%,End tidal sevoflurane 2.4%

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Age 3-7 yrs. 2. ASA physical status 1-2 3. Undergoing unilateral inguinal hernia repair/herniotomy at Han hospital 4. Surgery under anesthesia technique : General anesthesia with LMA with spontaneous ventilation with QLB type 2

Exclusion criteria

Exclusion criteria: 1. Obesity 2. Difficult airway is predicted 3. Allergy to : Midazolam, Fentanyl, Propofol, Dexmedetomidine, Bupivacaine, Ondansetron 4. Full stomach 5. Bradycardia

Design outcomes

Primary

MeasureTime frame
Smooth Laryngeal airway removal Emergence period, at post anesthetic care unit Incidence of perioperative respiratory adverse events

Secondary

MeasureTime frame
Incidence of perioperative adverse events Emergence, at post anesthetic care unit Incidence of perioperative adverse events

Countries

Thailand

Contacts

Public ContactKanokphol Singtana

Department of anesthesia, Nan hospital

kanokphol_yai@outlook.com054719000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026