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Hypothyroidism and osseointegration

The Effect of Hypothyroidism Treatment on Dental Implant Osseointegration Success

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20260215004
Enrollment
125
Registered
2026-02-15
Start date
2015-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypothyroid patients under medical treatment Hypothyroid patients not receiving medical treatment Healthy patients (control group) Hypothyroidism treatment Dental implant

Interventions

Hypothyroid patients using medication,Hypothyroid patient not using medication,Systemically healthy group with no systemic diseases
Screening,Screening,Screening
Hypothyroid patients using medication,Hypothyroid patient not using medication,Control group

Sponsors

Akdeniz University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Patients who have undergone dental implant treatment, are using hypothyroidism medication, and have completed at least one year since implant loading 2.Absence of any systemic disease and/or medical therapy that may affect wound healing or impair osseointegration 3.No requirement for bone augmentation and/or reduction procedures 4.Completion of periodontal therapy and/or being in the maintenance phase prior to implant placement surgery 5.Dental implants placed in the mandibular posterior region (premolar and molar areas) 6.Patients who have provided written informed consent 7.Individuals classified as ASA I or ASA II according to the American Society of Anesthesiologists (ASA) classification

Exclusion criteria

Exclusion criteria: 1.Patients who underwent immediate implant placement 2.Patients with known medical conditions that may negatively affect bone metabolism (vitamin D deficiency, osteomalacia, osteoporosis, Paget's disease, diabetes) 3.Patients with a history of chemotherapy and/or radiotherapy 4.Patients classified as ASA III or ASA IV according to the American Society of Anesthesiologists (ASA) 5.Pregnancy or lactation 6.Alcoholism 7.Smoking 8.Patients using immunosuppressive, antithrombotic, antiepileptic drugs, corticosteroids, proton pump inhibitors, bisphosphonates, or medications used for asthma or high cholesterol 9.Uncontrolled periodontal disease

Design outcomes

Primary

MeasureTime frame
the ability to perform prosthetic restoration 3 months osseointegration

Secondary

MeasureTime frame
Fractal Analysis 3 months Fractal Dimension

Countries

Turkey

Contacts

Public ContactBerkay Ozen

Akdeniz Universitesi Dis Hekimligi Fakultesi Agiz, Dis ve Cene Cerrahisi Anabilim Dali

bky23gs@gmail.com5349244645

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026