Brain parameters in fetuses with growth restriction different from normal growth Fetal Growth Restriction (FGR),Fetal Brain Biometry,Prenatal Ultrasound
Conditions
Interventions
fetuses with growth restriction ,EFW below P3 or P3-P10 with abnormal Doppler,fetuses with normal growth ,EFW normal P10-P90
Diagnostic,Diagnostic
fetuses with growth restriction,fetuses with normal growth
Sponsors
Khon Kaen University, Thailand
Eligibility
Sex/Gender
Female
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: General inclusion criteria 1.Singleton pregnant women aged greater than or equal to 18 years with informed consent 2.gestational age of 26 to 28 weeks were included 3.Gestational age was confirmed by first trimester ultrasonography using crown rump length. 4.Participants received antenatal care and planned delivery at Srinagarind Hospital, Faculty of Medicine, Khon Kaen University, or Khon Kaen Hospital. The control group comprised 1.pregnant women with normally grown fetuses 2. without fetal brain, cardiac, or other structural abnormalities 3.Controls were matched with the study group by gestational age, maternal age, and timing of fetal brain ultrasound examination. 4.Control participants underwent three fetal ultrasound examinations or at least two of three. The study group included 1.pregnant women diagnosed with fetal growth restriction at 26 to 28 weeks gestation 2.who underwent three fetal ultrasound examinations or at least two of three.
Exclusion criteria
Exclusion criteria: 1.Fetuses with confirmed genetic or chromosomal abnormalities identified through prenatal diagnostic testing 2.Fetuses with structural anomalies and/or other congenital malformations detected on prenatal ultrasonography
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biparietal diameter at 6 months after end of the intervention centimeter | — |
Secondary
| Measure | Time frame |
|---|---|
| Head circumference at 6 months after end of the intervention centimeter,Lateral ventricle at 6 months after end of the intervention centimeter,Sylvian fissure at 6 months after end of the intervention centimeter,Insular depth at 6 months after end of the intervention centimeter,Transverse cerebellar diameter at 6 months after end of the intervention centimeter,Frontal antero-posterior diameter at 6 months after end of the intervention centimeter,Occipito-frontal diameter at 6 months after end of the intervention centimeter | — |
Countries
Thailand
Contacts
Public ContactSiwanut Nakagul
Srinagarind Hospital Faculty of Medicine, Khon Kaen University
Outcome results
None listed