pre elderly and elderly with muscle health problems Sarcopenia, Plant-based protein, L-theanine, GABA, Branched-chain amino acid
Conditions
Interventions
Participants consume a regular cookie (commercially available crispy cookie) 2 times per day.,Participants consume high-protein plant-based cookies enriched with L-Theanine and GABA extracts 2 times
Sponsors
National Research Council of Thailand
Program Management Unit for Competitiveness (PMU-C)
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Sensory Acceptance Test 1. Male or female, Thai nationality, aged equal or more than 50 years. 2. No sensory impairments (taste, smell, vision, or hearing) that could affect sensory evaluation. 3. Having low muscle strength, low muscle mass, or low physical performance in at least one indicator according to the Asian Working Group for Sarcopenia (AWGS) 2025 criteria. 4. Able to read and write Thai. 5. Willing to participate and comply with the study protocol. 6. Have prior experience consuming cookies. Clinical Outcome Study (Effect of Product Consumption on Clinical Health Changes) 1. Male or female, Thai nationality, aged equal or more than 50 years. 2. Having low muscle strength, low muscle mass, or low physical performance in at least one indicator according to the AWGS 2025 criteria. 3. Able to read and write Thai. 4. Not engaged in night-shift work.
Exclusion criteria
Exclusion criteria: Sensory Acceptance Test 1. History of food allergy to any ingredients in the developed cookie product. 2. Presence of severe illness or uncontrolled chronic disease that may affect safety or participation, such as: Requiring frequent hospitalization, Unable to perform activities of daily living independently, Uncontrolled medical conditions (e.g., severe heart failure, end-stage renal disease, or cancer under active treatment) 3.Current smokers and regular alcohol consumers (equal or more than 3 times/week). 4. Pregnant, planning to become pregnant within 6 months, or currently breastfeeding. Clinical Outcome Study (Effect of Product Consumption on Clinical Health Changes) 1. Participants will be excluded if they meet any of the following criteria: 2. History of food allergy to any ingredients in the developed cookie product. 3. Presence of severe illness or uncontrolled chronic disease that may affect safety or participation, such as: Requiring frequent hospitalization, Unable to perform activities of daily living independently, Uncontrolled medical conditions (e.g., severe heart failure, end-stage renal disease, or cancer under active treatment) 4. Current smokers and regular alcohol consumers (equal or more than 3 times/week). 5. Pregnant, planning to become pregnant within 6 months, or currently breastfeeding. 6. Currently receiving medications for sarcopenia or insomnia, or regularly using laxatives.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition and anthropometry, muscle strength, Biochemical assessment. 3 months bioelectrical impedance analysis, Hand grip, Blood collection | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life, sleep quality, bowel movement 3 months World Health Organization Quality of Life scale, The Pittsburgh Sleep Quality Index, The Bristol Stool Chart | — |
Countries
Thailand
Contacts
Public ContactSirichan Ratanachotchuang
Department of Nutrition, Faculty of Public Health, Mahidol University
Outcome results
None listed