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Efficacy and Safety of 0.1% Topical Finasteride Spray for Male Eyebrow Hypotrichosis: A Randomized, Double-Blind, Split-Face Pilot Study

Efficacy of 0.1% Topical Finasteride Spray for Male Eyebrow Hypotrichosis: A Randomized, Split-Face, Placebo-Controlled Pilot Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260210009
Enrollment
8
Registered
2026-02-10
Start date
2025-06-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eyebrow hypotrichosis Eyebrows Hypotrichosis Finasteride Topical administration Hair growth Cosmetic dermatology

Interventions

Topical finasteride spray 0.1% applied twice daily to the randomized eyebrow for 12 weeks.,Vehicle placebo spray applied twice daily to the contralateral eyebrow for 12 weeks.
Placebo Comparator Drug,Placebo Comparator Drug
Topical finasteride 0.1% spray,Placebo spray

Sponsors

Mae Fah Luang University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Male participants aged 18 to 45 years with mild to moderate eyebrow hypotrichosis; good general health; willingness to comply with study procedures; ability to provide written informed consent.

Exclusion criteria

Exclusion criteria: Presence of dermatologic or systemic diseases affecting eyebrow hair growth, including alopecia areata, frontal fibrosing alopecia, thyroid disease, autoimmune disorders, or infections; history of eyebrow surgery or cosmetic procedures; use of topical or systemic agents affecting hair growth within the previous 6 months; known hypersensitivity to finasteride or study ingredients; contraindications to topical finasteride.

Design outcomes

Primary

MeasureTime frame
Change in global eyebrow appearance Week 12 Standardized photographic assessment using the Global Eyebrow Assessment (GEBA) scale

Secondary

MeasureTime frame
Change in eyebrow hair count Week 12 Hair count measured by digital dermoscopy

Countries

Thailand

Contacts

Public ContactBhakinai Temnithikul

MFU

Dr.bhakinai@gmail.com0817192567

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026