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Drinking coconut water before surgery to reduce complications and improve recovery

Effect of pre-procedures carbohydrate loading (coconut water) in elective general surgery , gut endoscopy, and aortic aneurysm surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260202009
Enrollment
812
Registered
2026-02-02
Start date
2022-10-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical patients Perioperative care Preoperative fasting Postoperative complications Aspiration pneumonia Surgical site infection Coconut water Carbohydrate loading Preoperative nutrition Enhanced recovery Anesthesia Surgery Endoscopy Aortic aneurysm

Interventions

Participants receive oral coconut water 250 ml at 20 00 on the evening before surgery and an additional dose 2 to 4 hours before anesthesia as a preoperative carbohydrate drink in addition to standard
Experimental Dietary Supplement,No Intervention No treatment
Coconut water carbohydrate loading,Standard preoperative fasting

Sponsors

Department of Surgery, Faculty of Medicine Ramathibodi Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Adults aged 18 to 65 years 2. Patients undergoing elective general surgery between October 2022 and May 2024 3. Patients who provide written informed consent by themselves or their legally authorized representatives

Exclusion criteria

Exclusion criteria: 1. Known allergy to coconut 2. Hemodynamic instability or shock 3. Immunocompromised status and type 2 diabetes mellitus with HbA1c 7 percent or higher 4. Impaired consciousness 5. Obesity 6. Gastrointestinal obstruction 7. Conditions associated with a high risk of aspiration, such as bowel obstruction or gastroesophageal reflux disease 8. Participants who decline or withdraw from the study

Design outcomes

Primary

MeasureTime frame
Aspiration pneumonia At 6, 24, 48, and 72 hours after surgery Chest X-ray

Secondary

MeasureTime frame
Quality of recovery At 24, 72 hours, and 2 weeks after surgery QOR 35 questionnaire score

Countries

Thailand

Contacts

Public ContactChairat Supsamutchai

Faculty of Medicine Ramathibodi Hospital

chairat.sup@mahidol.ac.th022011315

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026