allergic rhinitis A-Pai-Sa-li herbal remedy, Allergic rhinitis
Conditions
Interventions
A-Pai-Sa-Li herbal remedy, 500 mg per capsule, 4 capsules twice daily before breakfast and dinner for 30 days.,Placebo capsules, 500 mg, 4 capsules twice daily before breakfast and dinner for 30 days
Experimental Drug,Placebo Comparator Drug
A-Pai-Sa-Li herbal remedy,Placebo
Sponsors
Thai traditional medicine knowledge fund
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Male or female, aged 20-70 years. 2. Diagnosed with moderate-severe upper respiratory tract allergic disease according to the ARIA guideline 3. Pre-project blood test results as follows: eGFR more than60 mL/min AST, ALT less than 3 times the upper range Hb more than 10 g/dL 4. Women of reproductive age must have a negative urine pregnancy test. 5. Willing and willing to participate in the project and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with liver and kidney disorders 2. Patients with cardiovascular disease, taking anticoagulants, or anticoagulants, such as warfarin or aspirin 3. Patients with upper respiratory disease or who have undergone previous procedures 4. Patients with a history of herbal allergy or who have used other herbs within the past 2 weeks 5. Patients who have consumed alcohol within the month prior to and during the project 6. Patients with a history of drug use 7. Pregnant and breastfeeding women 8. Participants in other research projects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in total nasal symptom score Baseline, Day 14, Day 30 The nasal symptom record form.,Change in mean daily nasal symptom score Baseline, Day 14, Day 30 The daily nasal symptom diary. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life at 14 days and 30 day after start treatment Rhinoconjunctivitis Quality of Life Questionnaire (RCQ-36),Safety outcome From baseline to end of treatment. Number of adverse event, liver and kidney function tests (AST, ALT, eGFR) | — |
Countries
Thailand
Contacts
Public Contactsurasak imiam
phrapokklao hospital
Outcome results
None listed