Patients who do not have keratinized tissue or attached gingiva keratinized tissue, attached gingiva
Conditions
Interventions
A periosteal recipient bed is going to be prepared by a mean of split-thickness flap. Two vertical incisions from the incised gingival margin into the alveolar mucosa will be made to outline the recip
Free gingival graft (FGG),xenogenic collagen matrix
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age: Patients aged 18 years or older 2. Dental Condition: Presence of single-rooted teeth with a keratinized tissue width (KTW) of 1 mm on the buccal aspect in at least two quadrants. Teeth must be vital or have successfully completed endodontic treatment, with no evidence of root surface caries. The selection of surgical sites will be based on the patient's chief complaint and clinical indications for KTW augmentation. In cases where the surgical site is within the esthetic zone (visible during smiling), the research team will inform the patient and obtain voluntary consent prior to the procedure. 3. A pre-operative full-mouth Plaque Score of 20% 4. A pre-operative full-mouth Bleeding on Probing (BOP) score of 20%. 5. Smoking Status: Non-smokers or smokers who are able to abstain from smoking for at least 2 weeks post-surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with inadequate tissue thickness or volume at the palatal donor site. 2. Patients with active or untreated periodontitis. 3. Patients who have previously undergone surgical procedures at the intended recipient or donor sites. 4. Patients with a history of using medications associated with gingival enlargement within the past 6 months, including phenytoin, calcium channel blockers, and cyclosporine. 5. Patients with a history of hypersensitivity to medications prescribed during the study. 6. Patients who have uncontrolled systemic diseases, including immunodeficiency disorders and uncontrolled chronic conditions. 7. Patients with a Fasting Blood Sugar (FBS) level more than 154 mg/dl on the day of surgery (equivalent to HbA1c 7%) 8. Patients with a CD4 count more than 200 cells/microliter within 3 months prior to surgery, as this significantly impacts post-operative wound healing 9. Patients in the active infectious stage or those with a history of hepatitis within the last 3 months, due to the high risk of viral transmission during dental procedures 10. Other Conditions: Cardiovascular diseases or blood coagulation disorders are not absolute contraindications 11. Patients who are currently pregnant or breastfeeding. 12. Patients with religious constraints regarding the use of porcine-derived materials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Keratinized tissue width at 6 months after end of the intervention millimeter/use periodontal probe to measure the parameters | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactThitiwan Buranavichetkul
Mahidol university
Outcome results
None listed