Adult cancer patients receiving chemotherapy. Hospitalized patients for bone marrow transplantation mucositis Triphala extract mucoadhesive
Conditions
Interventions
Mucoadhesive Triphala extract
Oral rinse 4 times a day for 21 days ,Betadine oral rinse and oral hygiene
Experimental Other,Active Comparator Other
Triphala extract,Standard of care
Sponsors
Agricultural Research Development Agency
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.18 years old or older 2.multiple myeloma patients receiving high dose melphalan as chemotherapy. 3.Hospitalized patients in the bone marrow transplantation unit. 4.Eastern Co-operation Oncology Group Performance Status (ECOG-PS) from 0-2 5.No history of mucositis 6.Ability to provide informed consent.
Exclusion criteria
Exclusion criteria: 1.Known allergy to herbal products or components of the investigational product. 2.Unable to use products as directed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall incidence of all grade mucositis at 14 days 14 days after intervention number of patients | — |
Secondary
| Measure | Time frame |
|---|---|
| overall incidence of all grade mucositis 7 and 21 days after intervention number of patients ,pain score (if any) day 1-21 pain score from 1-10 ,incidence of oral infection day 1-21 number of patients ,time to mucositis day 1-21 time (days),incidence of adverse reaction day 1-21 number of ADR | — |
Countries
Thailand
Contacts
Public ContactJennis Meanwatthana
Mahidol University
Outcome results
None listed