The Effects of Oilgo-Fucoidan on Immune Status, Inflammato-ry Response, and Heavy Metal Concentrations in Patients with Chronic Respiratory Diseases Associated with Air Pollution in Central Taiwan

The oligo Fucoidan supplement improve the immune response, inflammatory status, oxidative stress, antioxidant capacity and heavy metal in patients of air pollution related chronic lung inflammation.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

TCTR

Registry ID

TCTR20260126009

Enrollment

Registered

2026-01-26

Start date

2022-01-22

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Respiratory Diseases PM2.5, chronic respiratory diseases, oligo-fucoidan, immune responses, inflammation.

Interventions

All enrolled participants received conventional therapy for chronic pulmonary diseases and oral supplementation with OF at a dose of 550 mg per tablet, two tablets twice daily, for 12 weeks.

Experimental Dietary Supplement

Oligo-Fucoidan

Eligibility

Sex/Gender

All

Age

20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. chronic bronchitis 2.emphysema 3. asthma 4.chronic obstructive pulmonary disease

Exclusion criteria

Exclusion criteria: 1.malignancy 2. infection 3.pregnancy and breastfeeding 4. receiving immunosuppressants other than steroids and bronchodilators 5. other systemic clinical immune diseases.

Design outcomes

Primary

Measure	Time frame
inflammation 12 weeks immunosorbent assay (ELISA),immune responses 12 weeks flow cytometry	—

Secondary

Measure	Time frame
heavy metals 12 weeks flame atomic absorption spectrometry	—

Countries

Taiwan

Contacts

Public ContactJueiNan cho

Hungkuang University

sec@hk.edu.tw0426318652

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026