This research determined the effect of southern food containing curcumin on changes in blood sugar levels and insulin response in humans. Therefore, the food developed was used for testing. Turmeric, Curcuminoid , Southern Thai food , Health Claims , Rice noodle in fish curry sauce
Conditions
Interventions
This research involves consuming a ready-to-eat food product that may help improve diabetes management. However, there are other treatment options available for diabetes. Therefore, it is recommended
Experimental Drug,Placebo Comparator Drug
High dose curcuminoids,Placebo
Sponsors
Program Management Unit for Competitiveness (PMUC) and Center of Excellence in Functional Foods and Gastronomy, Faculty of Agro-Industry, Prince of Songkla University
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Age from 35-60 years 2. Having Prediabetes according to the traditions of the Association of America (ADA), USB must have the qualifications to receive high praise... o Fasting blood sugar level (FPG) for at least 6 hours is between 100-125 mg/dL. o Blood sugar levels after ingesting 75 grams of glucose at 2 hours (OGTT) were between 140-199 mg/dL. o have an HbA1c level of 5.7-6.4% 3. The body mass index (BMI) value is in the range of 23.0-30.0 kg/m2. 4. People at risk for type 2 diabetes include a history of gestational diabetes. (Gestational, GDM) or a history of impaired glucose tolerance or a history of impaired fasting plasma glucose
Exclusion criteria
Exclusion criteria: 1. Have FPG level greater than or equal to126 mg per dL OGTT at 2 hours greater than or equal to200 mg per dL and HbA1c greater than or equal to6.5 percent. 2. Have congenital disease and regularly receive medications such as sugar-lowering drugs anti-platelet drugs angiotensin-converting enzyme inhibitors (angiotensin-converting enzyme inhibitors) angiotensin II receptor antagonists fenofibrate atorvastatin rosuvastatin and Fluvastatin etc. except for birth control pills. 3. People with serum creatinine greater than or equal to 2.0 mg per dl or who are undergoing dialysis. 4. People with liver enzyme alanine aminotransferase (ALT)greater than or equal to3 times the normal range. 5. People with secondary causes of hyperglycemia such as taking steroids or having pancreatic cancer. 6. People with acute infections or chronic inflammatory diseases (cancer, rheumatoid arthritis) 7. People with gallbladder disease or a history of gallbladder surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting plasma glucose (FBG) 12 week To evaluate the effectiveness of Southern Thai Fish Soup in reducing fasting plasma glucose and inflammatory markers such as C-reactive protein (CRP) in pre-diabetic condition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin, cholesterol, triglyceride, HbA1c, CRP, IL-6 (BUN and creatinine) 12 week To evaluate the effectiveness of Southern Thai Fish Soup in reducing fasting plasma glucose and inflammatory markers such as C-reactive protein (CRP) in pre-diabetic condition. | — |
Countries
Thailand
Contacts
Public ContactPreeyabhorn Detarun
Faculty of Agro-lndustry , Prince of Songkla University
Outcome results
None listed