Skip to content

External validation of the prediction model for diagnosing bipolar depressive disorder in adult patients with depressive disorder

External validation of the prediction model for diagnosing bipolar depressive disorder in adult patients with depressive disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20260124002
Enrollment
227
Registered
2026-01-24
Start date
2026-02-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with a major depressive episode who were diagnosed with major depressive disorder or bipolar disorder Clinical Prediction Rule

Interventions

Patients diagnosed with major depressive disorder.,Patients diagnosed with bipolar disorder who had experienced or were currently experiencing a major depressive episode, according to the ICD10 and DS
Diagnostic,Diagnostic
Unipolar depressive disorder ,Bipolar disorder

Sponsors

Faculty of Medicine Naresuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Case Group (Bipolar Disorder) 1.Patients diagnosed with bipolar disorder who had experienced or were currently experiencing a major depressive episode, according to the ICD10 and DSM5 diagnostic criteria. 2.Patients who were mentally alert and cognitively intact, and able to read, write, and communicate in Thai. 3.Patients aged 18 to 60 years. Control Group (Unipolar Depressive Disorder) 1.Patients diagnosed with major depressive disorder. 2.Patients who were mentally alert and cognitively intact, and able to read, write, and communicate in Thai. 3.Patients aged 18 to 60 years.

Exclusion criteria

Exclusion criteria: Exclusion Criteria Case Group (Bipolar Disorder) 1.Patients with psychiatric or medical emergencies requiring immediate treatment. 2.Patients diagnosed with schizophrenia, schizoaffective disorder, neurodevelopmental disorders (including intellectual disabilities and autism spectrum disorder), neurocognitive disorders (including delirium and dementia), stroke, or traumatic brain injury. 3.Patients who were currently experiencing psychotic symptoms. 4.Patients with current substance use, including alcohol, cannabis, methamphetamine, tobacco/nicotine, opioids and their derivatives, hallucinogens, or inhalants, or those who had ceased substance use within the past one month. Control Group (Unipolar Depressive Disorder) 1.Patients with a history of manic or hypomanic episodes not attributable to antidepressant treatment, diagnosed according to ICD10 and DSM5 criteria. 2.Patients with psychiatric or medical emergencies requiring immediate treatment. 3.Patients diagnosed with schizophrenia, schizoaffective disorder, neurodevelopmental disorders (including intellectual disabilities and autism spectrum disorder), neurocognitive disorders (including delirium and dementia), stroke, or traumatic brain injury. 4.Patients who were currently experiencing psychotic symptoms. 5.Patients with current substance use, including alcohol, cannabis, methamphetamine, tobacco/nicotine, opioids and their derivatives, hallucinogens, or inhalants, or those who had ceased substance use within the past one month.

Design outcomes

Primary

MeasureTime frame
Diagnosis bipolar disorder according to the ICD10 and DSM5 diagnostic criteria. Cros-sectional (Information was collected at the time of data collection interview.) Area Under the Receiver Operating Characteristic curve,calibration slope,calibration in the large (CITL)

Secondary

MeasureTime frame
NA NA NA

Countries

Thailand

Contacts

Public ContactAree Hinphet

Faculty of Medicine, 99 Moo 9, Tha Pho Amphoe Mueang Phitsanulok Phitsanulok 65000 THAILAND

areeh@nu.ac.th055965532

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026