Unresectable PDAC EUS RFA, RT, unresectable PDAC.
Conditions
Interventions
EUS-RFA is a new treatment. This minimally invasive modality applies electromagnetic energy to induce thermal injury within the target tissue, resulting in coagulative necrosis of tumor cells,Conventi
Treatment,Treatment
EUS-RFA ,RT
Sponsors
None
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with unresectable PDAC, defined as stage III locally advanced or stage IV metastatic pancreatic cancer according to the AJCC 8th edition classification 2. Patients receiving concurrent chemotherapy
Exclusion criteria
Exclusion criteria: 1. Uncorrectable coagulopathy (INR >1.5 or platelet < 50,000/ml) 2. Massive ascites 3. Clinically unstable for EUS-RFA or RT 4. Eastern Cooperative Oncology Group (ECOG) performance status more than 3 5. Life expectancy of less than 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression free survival year year | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall survival year year,Radiologic response 3,6,12 months Percentage,Adverse events All time Number | — |
Countries
Thailand
Contacts
Public ContactKanya Hirunrattanaporn
Chulalongkorn
Outcome results
None listed