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Effects of a Two-Week Neuromuscular Exercise Program Compared to Resistance and Flexibility Exercises on Postural Stability during Standing, Posture, and Postural Tremor in Individuals with Parkinsons Disease: A Randomized Controlled Trial

Effects of a Two-Week Neuromuscular Exercise Program Compared to Resistance and Flexibility Exercises on Postural Stability during Standing, Posture, and Postural Tremor in Individuals with Parkinsons Disease: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260122015
Enrollment
34
Registered
2026-01-22
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson disease Parkinson disease Neuromuscular exercise Balance Sensorimotor integration Exercise therapy

Interventions

The principle of exercise involves performing movements in closed kinetic chain positions, where the body is placed under weight-bearing conditions as much as possible to enhance sensorimotor control.
Experimental Other,Active Comparator Other
Neuromuscular exercise,Resistance and Flexibility Exercises

Sponsors

Faculty of Physical Therapy, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Parkinson disease at modified Hoehn and Yahr stage 2-3 2.Age 40-70 years 3.Stable Parkinson disease medication 4.Individuals with postural abnormalities 5.Ability to stand independently and ambulate at least 10 meters without the use of an assistive device 6.Able to follow commands and instructions

Exclusion criteria

Exclusion criteria: 1.History of cognitive impairment or dementia, as assessed by the Montreal Cognitive Assessment 5 minute 2.History of neurological deficits 3.History of cardiopulmonary diseases 4.History of musculoskeletal conditions that significantly limit posture, balance, or gait 5.Individuals with severe motor symptoms or motor complications 6.Sustained depression and/or anxiety measured by Hospital Anxiety and Depression Scale 7.History of brain surgery 8.Any medical or surgical interventions 9.Visual or hearing impairments 10.Inability to safely participate in telehealth-based exercise sessions

Design outcomes

Primary

MeasureTime frame
Postural stability Pre-test (baseline) and post-intervention (2 weeks) Postural stability measured by force platform recording center of pressure displacement; parameters: 95% confidence ellipse area (mm2) and path length (mm).

Secondary

MeasureTime frame
1.Range of motion 2.Postural tremor Pre-test (baseline) and post-intervention (2 weeks) 1.Range of motion measured with inertial measurement units for neck, upper back, and kyphosis angles (degrees). 2.Postural tremor measured with Arm Stability Test, total arm movement path (degrees).

Countries

Thailand

Contacts

Public ContactPabtawan Warngchann

Faculty of Physical Therapy, Mahidol University

pabtawan.war@student.mahidol.edu024415450

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026