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Effect of high-flow nasal canula (HFNC) versus Non-rebreather oxygen face mask on partial pressure of arterial oxygen in Non-intubated video-assisted thoracic surgery (NIVATS): a randomized controlled trial

Effect of high-flow nasal canula (HFNC) versus Non-rebreather oxygen face mask on partial pressure of arterial oxygen in Non-intubated video-assisted thoracic surgery (NIVATS): a randomized controlled trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20260122013
Enrollment
68
Registered
2026-01-22
Start date
2022-05-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergoing elective non-intubated video-assisted thoracic surgery (NIVATs) with any lung condition. Non-intubated video-assisted thoracic surgery, NIVATs, high-flow nasal canula, HFNC,

Interventions

non-rebreather oxygen face mask with an oxygen flow of 15 LPM apply during NIVATS. Arterial blood gas (ABG) samples were collected at the following time points: (1) baseline (room air) before inductio
(2) at 10 minutes after induction with a BIS value of 40-60 during closed chest
(3) at 15 minutes after open chest
(4) at 30 minutes after open chest
(5) at 15 minutes after the resumption of two-lung ventilation
and (6) at 30 minutes after the resumption of two-lung ventilation.,HFNC with an FiO2 of 0.95 at 30 LPM apply during NIVATS. Arterial blood gas (ABG) samples were collected at the following time point
and (6) at 30 minutes after the resumption of two-lung ventilation.
non-rebreather oxygen face mask ,high-flow nasal canula (HFNC)

Sponsors

Faculty of Medicine, Vajira Hospital, Navamindradhiraj University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: adults aged > 18 years scheduled for elective Non-Intubated Video-Assisted Thoracic Surgery (NIVATs).

Exclusion criteria

Exclusion criteria: emergency surgery, severe obstructive or restrictive pulmonary diseases, preoperative oxygen saturation (SpO2) <90% or partial pressure of arterial oxygen (PaO2) < 60mmHg, risk aspiration, severe pulmonary adhesion, bilateral pulmonary diseases, history of previous lung resection, abnormal airway anatomy, suspected difficult intubation, body mass index (BMI) > 35 kg/m2, pregnancy, and an anticipated surgical duration of less than 30 minutes (making it impossible to complete the study protocol).

Design outcomes

Primary

MeasureTime frame
Oxygenation parameters baseline (RA), 10 min after induction with closed chest,15 min and 30 min after open chest, 15 min and 30 min after resumption of two-lung ventilation. arterial blood gas

Secondary

MeasureTime frame
lung collapse quality 30 min after open chest 4-point Likert scale

Countries

Thailand

Contacts

Public Contactratchaya weerayutwattana

Faculty of Medicine, Vajira Hospital, Navamindradhiraj University

ratchaya@nmu.ac.th66897566687

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026