Hemodynamic instability (maternal hypotension ),associted with spinal anesthesia in cesarean delivery. Cesarean section spinal anesthesia Ropivacaine Bupivacaine Local anesthetic Maternal hypotension
Conditions
Interventions
Spinal anesthesia with 0.75% isobaric bupivacaine 20-25 mg add morphine 0.15 mg,Spinal anesthesia with 0.5% Hyperbaric Bupivacaine 10-12 mg add morphine 0.15 mg
Experimental Drug,Active Comparator Drug
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. patient under going elective ceserean section with spinal anesthesia 2. Age between 18-40 years old 3.ASA class I - II 4. Gestational age 37-42 week 5. Singleton pregnancy 6. consent to participate in research
Exclusion criteria
Exclusion criteria: 1. Allergy / advrese reaction to anesthetic agent 2. Patient who contraindicated to spinal anesthesia with intrathecal morphine 3.Patient who has obsteric complication 4.Patient who has chronic pain or chronic opioid used 5. Patient who cannot communicated in Thai 6. BMI >= 40 kg/m2 7. Patient refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maternal hypotension 2 hours Maternal blood pressure | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal bradycardia 2 hours Maternal Heart rate,Need for vasopressor used 2 hours Dose of vasopressor ,Duration of blockage 24 hours time of blockade regression ,neonatal outcome 1 and 5 minutes after birth APGAR score | — |
Countries
Thailand
Contacts
Public ContactPhanuthep Chintanakul
Department of anesthesiology, Faculty of medicine ,Chulalongkorn university
Outcome results
None listed